Literature DB >> 26815666

Epidemiology of in-hospital trauma deaths.

R Lefering1, T Paffrath2, O Bouamra3, T J Coats4, M Woodford3, T Jenks3, A Wafaisade2, U Nienaber5, F Lecky3.   

Abstract

PURPOSE: About half of all trauma-related deaths occur after hospital admission. The present study tries to characterize trauma deaths according to the time of death, and, thereby, contributes to the discussion about factors considered as the cause of death.
METHODS: Data from two large European trauma registries (Trauma Registry of the German Society of Trauma Surgery, TR-DGU, and the Trauma Audit and Research Network, TARN) were analyzed in parallel. All hospital deaths with Injury Severity Score (ISS) > 9 documented between 2000 and 2010 were considered. Patients were categorized into five subgroups according to the time to death (0-6 h; 7-24 h; day 1-6; day 7-30; beyond day 30). Surviving patients from the same time period served as a control group.
RESULTS: In total, 6,685 and 6,867 non-survivors were included from the TR-DGU and TARN, respectively. The hospital mortality rate was between 15 and 17%. About half of all deaths occurred within the first 24 h after admission (TR-DGU: 54%; TARN: 45%). The earliest subgroup of trauma deaths showed the highest mean ISS and the highest rate of mass transfusions. Severe head injury was most frequently observed in the subgroup of day 1-6. Late deaths are associated with higher age and more complications (sepsis, multiple organ failure).
CONCLUSIONS: The time to death after severe trauma does not follow a trimodal distribution but shows a constantly decreasing incidence.

Entities:  

Keywords:  Cause of deaths; Mortality; Severe injuries; Trauma; Trauma registry

Year:  2011        PMID: 26815666     DOI: 10.1007/s00068-011-0168-4

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   3.693


  14 in total

1.  The Major Trauma Outcome Study: establishing national norms for trauma care.

Authors:  H R Champion; W S Copes; W J Sacco; M M Lawnick; S L Keast; L W Bain; M E Flanagan; C F Frey
Journal:  J Trauma       Date:  1990-11

2.  Epidemiology of traumatic deaths: comprehensive population-based assessment.

Authors:  Julie A Evans; Karlijn J P van Wessem; Debra McDougall; Kevin A Lee; Timothy Lyons; Zsolt J Balogh
Journal:  World J Surg       Date:  2010-01       Impact factor: 3.352

3.  Trauma. Accidental and intentional injuries account for more years of life lost in the U.S. than cancer and heart disease. Among the prescribed remedies are improved preventive efforts, speedier surgery and further research.

Authors:  D D Trunkey
Journal:  Sci Am       Date:  1983-08       Impact factor: 2.142

4.  A new approach to outcome prediction in trauma: A comparison with the TRISS model.

Authors:  Omar Bouamra; Alan Wrotchford; Sally Hollis; Andy Vail; Maralyn Woodford; Fiona Lecky
Journal:  J Trauma       Date:  2006-09

5.  Trauma deaths in a mature urban trauma system: is "trimodal" distribution a valid concept?

Authors:  Demetrios Demetriades; Brian Kimbrell; Ali Salim; George Velmahos; Peter Rhee; Christy Preston; Ginger Gruzinski; Linda Chan
Journal:  J Am Coll Surg       Date:  2005-09       Impact factor: 6.113

6.  Reduction in mortality of severely injured patients in Germany.

Authors:  Steffen Ruchholtz; Rolf Lefering; Thomas Paffrath; Hans Jörg Oestern; Edmund Neugebauer; Dieter Nast-Kolb; Hans-Christoph Pape; Bertil Bouillon
Journal:  Dtsch Arztebl Int       Date:  2008-03-28       Impact factor: 5.594

7.  Association of preexisting medical conditions with in-hospital mortality in multiple-trauma patients.

Authors:  Sebastian Wutzler; Marc Maegele; Ingo Marzi; Timo Spanholtz; Arasch Wafaisade; Rolf Lefering
Journal:  J Am Coll Surg       Date:  2009-05-28       Impact factor: 6.113

8.  Hemorrhage is More Prevalent than Brain Injury in Early Trauma Deaths: The Golden Six Hours.

Authors:  Vishal Bansal; Dale Fortlage; Jeanne G Lee; Todd Costantini; Bruce Potenza; Raul Coimbra
Journal:  Eur J Trauma Emerg Surg       Date:  2008-11-26       Impact factor: 3.693

9.  Applicability of the trimodal distribution of trauma deaths in a Level I trauma centre in the Netherlands with a population of mainly blunt trauma.

Authors:  C de Knegt; S A G Meylaerts; L P H Leenen
Journal:  Injury       Date:  2008-07-25       Impact factor: 2.586

10.  Trauma fatalities: time and location of hospital deaths.

Authors:  Demetrios Demetriades; James Murray; Kiriakos Charalambides; Kathy Alo; George Velmahos; Peter Rhee; Linda Chan
Journal:  J Am Coll Surg       Date:  2004-01       Impact factor: 6.113

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  29 in total

1.  Update of the trauma risk adjustment model of the TraumaRegister DGU™: the Revised Injury Severity Classification, version II.

Authors:  Rolf Lefering; Stefan Huber-Wagner; Ulrike Nienaber; Marc Maegele; Bertil Bouillon
Journal:  Crit Care       Date:  2014-09-05       Impact factor: 9.097

Review 2.  [Pathophysiology of multiple trauma : intensive care medicine and timing of treatment].

Authors:  S Wutzler; T Lustenberger; B Relja; M Lehnert; I Marzi
Journal:  Chirurg       Date:  2013-09       Impact factor: 0.955

3.  What are the differences in injury patterns of young and elderly traffic accident fatalities considering death on scene and death in hospital?

Authors:  Daniela Heinrich; Christopher Holzmann; Anja Wagner; Anja Fischer; Roman Pfeifer; Matthias Graw; Sylvia Schick
Journal:  Int J Legal Med       Date:  2017-02-08       Impact factor: 2.686

4.  Trauma registry comparison: six-year results in trauma care in Southern Finland and Germany.

Authors:  T Brinck; L Handolin; T Paffrath; R Lefering
Journal:  Eur J Trauma Emerg Surg       Date:  2014-11-14       Impact factor: 3.693

5.  Assessment of traumatic deaths in a level one trauma center in Ankara, Turkey.

Authors:  E D Arslan; E Kaya; M Sonmez; C Kavalci; A Solakoglu; F Yilmaz; T Durdu; E Karakilic
Journal:  Eur J Trauma Emerg Surg       Date:  2014-08-02       Impact factor: 3.693

Review 6.  Macrophages play an essential role in trauma-induced sterile inflammation and tissue repair.

Authors:  Moritz Peiseler; Paul Kubes
Journal:  Eur J Trauma Emerg Surg       Date:  2018-04-17       Impact factor: 3.693

Review 7.  Innate immune responses to trauma.

Authors:  Markus Huber-Lang; John D Lambris; Peter A Ward
Journal:  Nat Immunol       Date:  2018-03-05       Impact factor: 25.606

8.  Timing of mortality in pediatric trauma patients: A National Trauma Data Bank analysis.

Authors:  Cory McLaughlin; Jessica A Zagory; Michael Fenlon; Caron Park; Christianne J Lane; Daniella Meeker; Randall S Burd; Henri R Ford; Jeffrey S Upperman; Aaron R Jensen
Journal:  J Pediatr Surg       Date:  2017-10-08       Impact factor: 2.545

9.  Cause of death and time of death distribution of trauma patients in a Level I trauma centre in the Netherlands.

Authors:  K W W Lansink; A C Gunning; L P H Leenen
Journal:  Eur J Trauma Emerg Surg       Date:  2013-05-07       Impact factor: 3.693

Review 10.  [Diagnostics and treatment strategies for multiple trauma patients].

Authors:  R Pfeifer; H-C Pape
Journal:  Chirurg       Date:  2016-02       Impact factor: 0.955

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