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Literature DB >> 17690091

Enzymatic transition state theory and transition state analogue design.

Vern L Schramm¹.

Abstract

Mesh：

Substances：
Enzymes

Year: 2007 PMID： 17690091 DOI： 10.1074/jbc.R700018200

Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157

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Cited

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46 in total

1. A direct NMR method for the measurement of competitive kinetic isotope effects.

Authors: Jefferson Chan; Andrew R Lewis; Michel Gilbert; Marie-France Karwaski; Andrew J Bennet
Journal: Nat Chem Biol Date: 2010-04-25 Impact factor: 15.040

2. Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.

Authors: Yong Zhang; Vern L Schramm
Journal: J Am Chem Soc Date: 2010-06-30 Impact factor: 15.419

3. Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.

Authors: Myles B Poulin; Jessica L Schneck; Rosalie E Matico; Patrick J McDevitt; Michael J Huddleston; Wangfang Hou; Neil W Johnson; Sara H Thrall; Thomas D Meek; Vern L Schramm
Journal: Proc Natl Acad Sci U S A Date: 2016-01-19 Impact factor: 11.205

4. Transition state analysis of the arsenolytic depyrimidination of thymidine by human thymidine phosphorylase.

Authors: Phillip A Schwartz; Mathew J Vetticatt; Vern L Schramm
Journal: Biochemistry Date: 2011-02-03 Impact factor: 3.162

5. Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.

Authors: Keith Clinch; Gary B Evans; Richard F G Fröhlich; Richard H Furneaux; Peter M Kelly; Laurent Legentil; Andrew S Murkin; Lei Li; Vern L Schramm; Peter C Tyler; Anthony D Woolhouse
Journal: J Med Chem Date: 2009-02-26 Impact factor: 7.446

Enzymatic transition state theory and transition state analogue design.

1. A direct NMR method for the measurement of competitive kinetic isotope effects.

2. Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.

3. Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.

4. Transition state analysis of the arsenolytic depyrimidination of thymidine by human thymidine phosphorylase.

5. Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.

Review 6. Specificity in transition state binding: the Pauling model revisited.

Review 7. Experimental analyses of the chemical dynamics of ribozyme catalysis.

8. Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.

9. Beyond picomolar affinities: quantitative aspects of noncovalent and covalent binding of drugs to proteins.

Review 10. Glycosidase inhibition: assessing mimicry of the transition state.