Literature DB >> 176870

Biosynthesis of unsaturated fatty acids in cultured minimal deviations hepatoma 7288 C cells.

M J de Alaniz, G Ponz, R R Brenner.   

Abstract

Minimal Deviation Hepatoma 7288 C cells were cultured in confluent layer with labeled linoleic, alpha-linolenic, eicosa-8,11,14-trienoic and stearic acids. The cells in culture preserved their ability to convert stearic acid to oleic acid. They also synthesized arachidonic acid from linoleic acid or eicosa-8,11,14-trienoic acid. The conversion was very low with linoleic acid and high with eicosatrienoic acid. Eicosapentaenoic acid and other homologs of the alpha-linolenic acid family were synthesized from alpha-linolenic acid. The biosynthetic patterns were the cells was modified by the fatty acid composition of the media.

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Year:  1975        PMID： 176870

Source DB:  PubMed          Journal:  Acta Physiol Lat Am        ISSN： 0001-6764


  13 in total

1.  Uptake and metabolism of exogenous eicosa-8,11,14-trienoic acid in minimal deviation hepatoma 7288 C cells.

Authors:  G Gaspar; M J de Alaniz; R R Brenner
Journal:  Lipids       Date:  1975-12       Impact factor: 1.880

2.  Effect of "fasting" and different concentrations of glucose on alpha-linolenic acid metabolism in HTC cells. Correlation with the ultrastructural study.

Authors:  L A Gomez Dumm; M J Tacconi de Alaniz
Journal:  Mol Cell Biochem       Date:  1977-11-25       Impact factor: 3.396

3.  delta 15,18-tetracosadienoic acid content of sphingolipids from platelets and erythrocytes of animals fed diets high in saturated or polyunsaturated fats.

Authors:  R E Pitas; G J Nelson; R M Jaffe; R W Mahley
Journal:  Lipids       Date:  1978-08       Impact factor: 1.880

4.  Fatty acid uptake and metabolism in Hep G2 human-hepatoma cells.

Authors:  C Angeletti; M J de Alaniz
Journal:  Mol Cell Biochem       Date:  1995-02-23       Impact factor: 3.396

5.  Incorporation and metabolic conversion of saturated and unsaturated fatty acids in SK-Hep1 human hepatoma cells in culture.

Authors:  C A Marra; M J de Alaniz
Journal:  Mol Cell Biochem       Date:  1992-11-18       Impact factor: 3.396

6.  Effect of fatty acids of omega 6 series on the biosynthesis of arachidonic acid in HTC cells.

Authors:  M J de Alaniz; I N de Gómez Dumm; R R Brenner
Journal:  Mol Cell Biochem       Date:  1984-09       Impact factor: 3.396

7.  Inhibition of arachidonate biosynthesis in hepatoma tissue culture cells by 11-deoxycorticosterone-induced factor.

Authors:  C A Marra; M J de Alaniz
Journal:  Mol Cell Biochem       Date:  1991-04-24       Impact factor: 3.396

8.  Role of delta 9 desaturase activity in the maintenance of high levels of monoenoic fatty acids in hepatoma cultured cells.

Authors:  M J de Alaniz; C A Marra
Journal:  Mol Cell Biochem       Date:  1994-08-17       Impact factor: 3.396

9.  Role of fatty acids of (n-3) and (n-6) series on alpha-linolenic acid desaturation and chain elongation in HTC cells.

Authors:  M J de Alaniz; I N de Gómez Dumm
Journal:  Mol Cell Biochem       Date:  1990-03-05       Impact factor: 3.396

10.  Uptake and metabolism of eicosa-8, 11, 14-trienoic acid in normal hepatocytes and HTC cells.

Authors:  C A Marra; M J de Alaniz; R R Brenner
Journal:  Mol Cell Biochem       Date:  1985-01       Impact factor: 3.396
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