| Literature DB >> 17686381 |
Guido Grassi1, Francesca Arenare, Fosca Quarti Trevano, Raffaella Dell'Oro, And Giuseppe Mancia.
Abstract
High blood pressure represents one of the leading risk factors for the development of stroke and its recurrence. This explains why blood pressure control is a major objective of antihypertensive treatment, both in primary and secondary prevention of this cerebrovascular disease. This paper reviews the evidence provided by randomized clinical trials on the favorable effects exerted by blood pressure reduction on this end point. Emphasis is given to the results of recently published clinical trials documenting that drugs acting on the renin-angiotensin system may exert cerebrovascular protective effects additive to the ones associated with blood pressure reduction.Entities:
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Year: 2007 PMID： 17686381 DOI： 10.1007/s11906-007-0055-x
Source DB: PubMed Journal: Curr Hypertens Rep ISSN： 1522-6417 Impact factor: 5.369