Ing Tuan Tan1, Bok Yan Jimmy So. 1. Department of Surgery, National University Hospital, Singapore, Republic of Singapore. ingtuan@yahoo.com
Abstract
OBJECTIVE: Most clinicians perform surveillance after gastrectomy for gastric cancer. There is no consensus on the regimen, follow-up interval and choice of investigations. This study aims to review the long-term results of patients followed-up in our institution after gastrectomy for gastric cancer. METHODS: Patients with gastric carcinoma who had undergone gastrectomy between 1995 and 1998 were reviewed. The patients were assigned to either intensive or regular regimen based on the follow-up they had undergone. Intensive regimen included routine physical examination, serum tumor markers, and the use of computed tomography (CT) scan of more than once per year in the follow-up. RESULTS: A total of 102 patients were reviewed. Forty-nine patients received intensive and 53 patients received regular follow-up. Recurrences were detected earlier in the intensive group (11.5 vs. 19.2 months, P = 0.02). There was no difference in the length of survival in the two groups. Most recurrences (60%) were detected by CT scan. CONCLUSIONS: Intensive follow-up after gastrectomy resulted in the earlier detection of recurrences. However, there was no survival benefit from this regimen. A regimen based on symptoms and physical examination is adequate for most patients. CT was the most useful investigation for detection of recurrences.
OBJECTIVE: Most clinicians perform surveillance after gastrectomy for gastric cancer. There is no consensus on the regimen, follow-up interval and choice of investigations. This study aims to review the long-term results of patients followed-up in our institution after gastrectomy for gastric cancer. METHODS:Patients with gastric carcinoma who had undergone gastrectomy between 1995 and 1998 were reviewed. The patients were assigned to either intensive or regular regimen based on the follow-up they had undergone. Intensive regimen included routine physical examination, serum tumor markers, and the use of computed tomography (CT) scan of more than once per year in the follow-up. RESULTS: A total of 102 patients were reviewed. Forty-nine patients received intensive and 53 patients received regular follow-up. Recurrences were detected earlier in the intensive group (11.5 vs. 19.2 months, P = 0.02). There was no difference in the length of survival in the two groups. Most recurrences (60%) were detected by CT scan. CONCLUSIONS: Intensive follow-up after gastrectomy resulted in the earlier detection of recurrences. However, there was no survival benefit from this regimen. A regimen based on symptoms and physical examination is adequate for most patients. CT was the most useful investigation for detection of recurrences.
Authors: Leila Sisic; Moritz J Strowitzki; Susanne Blank; Henrik Nienhueser; Sara Dorr; Georg Martin Haag; Dirk Jäger; Katja Ott; Markus W Büchler; Alexis Ulrich; Thomas Schmidt Journal: Gastric Cancer Date: 2017-07-24 Impact factor: 7.370
Authors: Cynthia Villarreal-Garza; Miriam Rojas-Flores; Andrea Castro-Sánchez; Antonio R Villa; Luis García-Aceituno; Eucario León-Rodríguez Journal: Med Oncol Date: 2010-06-02 Impact factor: 3.064
Authors: Thiago Pereira Diniz; Wilson L da Costa; Camila Couto Gomes; Victor Hugo F de Jesus; Tiago C Felismino; Silvio Melo Torres; Héber S C Ribeiro; Alessandro L Diniz; André Luís de Godoy; Igor Correia de Farias; Emmanuel Dias-Neto; Maria Paula Curado; Felipe J F Coimbra Journal: Ann Surg Oncol Date: 2021-11-15 Impact factor: 5.344