Literature DB >> 17679068

Tl-201 stress tests and homeland security.

Lawrence T Dauer1, Matthew J Williamson, Jean St Germain, H William Strauss.   

Abstract

BACKGROUND: This study estimates the length of time a patient might trigger security radiation detection devices after thallium 201 cardiac imaging. The US Department of Homeland Security is supporting the purchase and deployment of radiation detection pagers and portal monitors. Concurrently, there are an increasing number of cardiac perfusion imaging studies being performed using Tl-201. Therefore there is a higher probability that patients who have undergone nuclear medicine procedures could trigger alarms resulting in security questions. METHODS AND
RESULTS: The length of time patients could trigger such devices is estimated based on the radiopharmacokinetics of Tl-201 and potential radioactive contaminants as well as the capabilities of current sensitive radiation detection devices, assuming the radioactive sources are distributed in and attenuated by the patient. It is estimated that patients may trigger portable pager devices for up to 33 days and may trigger portal detectors for up to 51 days after studies using Tl-201. This is much longer than length of time for a patient to trigger such alarms after technetium 99m myocardial imaging tests, which is potentially up to 6 days.
CONCLUSIONS: It should be standard practice for patients to be issued information cards that indicate the potential time for triggering security radiation detectors after diagnostic cardiac procedures involving the use of Tl-201 or other radiopharmaceuticals.

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Year:  2007        PMID: 17679068     DOI: 10.1016/j.nuclcard.2007.04.021

Source DB:  PubMed          Journal:  J Nucl Cardiol        ISSN: 1071-3581            Impact factor:   5.952


  17 in total

1.  Advances in radiation detection technologies for responders.

Authors:  Michael P Unterweger; Leticia S Pibida
Journal:  Health Phys       Date:  2005-11       Impact factor: 1.316

2.  Long term retention and excretion of 201Tl in a patient after myocardial perfusion imaging.

Authors:  E Blanchardon; C Challeton-de Vathaire; P Boisson; D Célier; J-C Martin; S Cassot; G Herbelet; D Franck; J R Jourdain; A Biau
Journal:  Radiat Prot Dosimetry       Date:  2005-01-25       Impact factor: 0.972

3.  Radioisotopes and airport security.

Authors:  M Bilal Iqbal; Rakesh Sharma; S Richard Underwood; Sam Kaddoura
Journal:  Lancet       Date:  2005 Jul 23-29       Impact factor: 79.321

4.  Pharmacokinetics of thallium-201 in normal individuals after routine myocardial scintigraphy.

Authors:  W Krahwinkel; H Herzog; L E Feinendegen
Journal:  J Nucl Med       Date:  1988-09       Impact factor: 10.057

5.  Radiation dose to patients from radiopharmaceuticals. A report of a Task Group of Committee 2 of the International Commission on Radiological Protection.

Authors: 
Journal:  Ann ICRP       Date:  1987

6.  Thallium stress tests and bank vaults.

Authors:  M E Levin; K C Fischer
Journal:  N Engl J Med       Date:  1988-09-01       Impact factor: 91.245

Review 7.  201Tl-labelled TlCl dosimetry revisited.

Authors:  F P Castronovo
Journal:  Nucl Med Commun       Date:  1993-02       Impact factor: 1.690

8.  Limits for intakes of radionuclides by workers. A report of committee 2 of the International Commission on Radiological Protection.

Authors: 
Journal:  Ann ICRP       Date:  1980

9.  Radiation-absorbed dose from 201Tl-thallous chloride.

Authors:  Stephen R Thomas; Michael G Stabin; Frank P Castronovo
Journal:  J Nucl Med       Date:  2005-03       Impact factor: 10.057

10.  Thallium-201 for medical use. Part 3: Human distribution and physical imaging properties.

Authors:  H L Atkins; T F Budinger; E Lebowitz; A N Ansari; M W Greene; R G Fairchild; K J Ellis
Journal:  J Nucl Med       Date:  1977-02       Impact factor: 10.057

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  1 in total

1.  Re: Tl-201 stress tests and homeland security.

Authors:  Bernard Gitler
Journal:  J Nucl Cardiol       Date:  2007 Nov-Dec       Impact factor: 5.952

  1 in total

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