| Literature DB >> 17676062 |
Xiaoyu Zhang1, Sophie Germann, Bartlomiej J Blus, Sepideh Khorasanizadeh, Valerie Gaudin, Steven E Jacobsen.
Abstract
Polycomb proteins are required for maintenance of silent chromatin states via histone H3 Lys27 trimethylation (H3K27me3) in animals, but homologs are not found in plant genomes. Using a DamID-chip method, we found that the Arabidopsis thaliana chromodomain-containing protein LHP1 colocalizes with H3K27me3 genome-wide. The LHP1 chromodomain also binds H3K27me3 with high affinity, suggesting that LHP1 has functions similar to those of Polycomb.Entities:
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Year: 2007 PMID： 17676062 DOI： 10.1038/nsmb1283
Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369