Literature DB >> 17675259

Mechanisms of immunomodulation by mesenchymal stem cells.

Katsutoshi Ozaki1, Kazuya Sato, Iekuni Oh, Akiko Meguro, Raine Tatara, Kazuo Muroi, Keiya Ozawa.   

Abstract

Mesenchymal stem cells (MSCs) have been identified in animals, especially in bone marrow. As stem cells, they have the ability to differentiate into multiple cell types. This potential raises exciting therapeutic possibilities. A recent report described the successful use of MSCs for the treatment of graft-versus-host disease; however, the scientific community has yet to define the molecular mechanisms of immunomodulation by MSCs. This review summarizes what is known and discusses the conflicting data with regard to the mechanisms of immunomodulation by MSCs.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17675259     DOI： 10.1532/IJH97.07003

Source DB:  PubMed          Journal:  Int J Hematol        ISSN： 0925-5710            Impact factor:   2.490


  19 in total

1.  Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells.

Authors:  Katarina Le Blanc; Ida Rasmusson; Berit Sundberg; Cecilia Götherström; Moustapha Hassan; Mehmet Uzunel; Olle Ringdén
Journal:  Lancet       Date:  2004-05-01       Impact factor: 79.321

2.  Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice.

Authors:  Muriel Sudres; Françoise Norol; Aurélie Trenado; Sylvie Grégoire; Frédéric Charlotte; Béatrice Levacher; Jean-Jacques Lataillade; Philippe Bourin; Xavier Holy; Jean-Paul Vernant; David Klatzmann; José L Cohen
Journal:  J Immunol       Date:  2006-06-15       Impact factor: 5.422

3.  Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2.

Authors:  Sangwon F Kim; Daniel A Huri; Solomon H Snyder
Journal:  Science       Date:  2005-12-23       Impact factor: 47.728

4.  Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease.

Authors:  Rosa Yañez; María Luisa Lamana; Javier García-Castro; Isabel Colmenero; Manuel Ramírez; Juan A Bueren
Journal:  Stem Cells       Date:  2006-07-27       Impact factor: 6.277

5.  Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients.

Authors:  Hillard M Lazarus; Omer N Koc; Steven M Devine; Peter Curtin; Richard T Maziarz; H Kent Holland; Elizabeth J Shpall; Philip McCarthy; Kerry Atkinson; Brenda W Cooper; Stanton L Gerson; Mary J Laughlin; Fausto R Loberiza; Annemarie B Moseley; Andrea Bacigalupo
Journal:  Biol Blood Marrow Transplant       Date:  2005-05       Impact factor: 5.742

6.  Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells.

Authors:  Kazuya Sato; Katsutoshi Ozaki; Iekuni Oh; Akiko Meguro; Keiko Hatanaka; Tadashi Nagai; Kazuo Muroi; Keiya Ozawa
Journal:  Blood       Date:  2006-09-19       Impact factor: 22.113

7.  Human mesenchymal stem cells modulate allogeneic immune cell responses.

Authors:  Sudeepta Aggarwal; Mark F Pittenger
Journal:  Blood       Date:  2004-10-19       Impact factor: 22.113

8.  Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness.

Authors:  Shaul Beyth; Zipora Borovsky; Dror Mevorach; Meir Liebergall; Zulma Gazit; Hadi Aslan; Eithan Galun; Jacob Rachmilewitz
Journal:  Blood       Date:  2004-10-28       Impact factor: 22.113

9.  Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation.

Authors:  Roland Meisel; Andree Zibert; Maurice Laryea; Ulrich Göbel; Walter Däubener; Dagmar Dilloo
Journal:  Blood       Date:  2004-03-04       Impact factor: 22.113

10.  Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone.

Authors:  Edwin M Horwitz; Patricia L Gordon; Winston K K Koo; Jeffrey C Marx; Michael D Neel; Rene Y McNall; Linda Muul; Ted Hofmann
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-25       Impact factor: 11.205
View more
  14 in total

1.  Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes.

Authors:  Paolo Fiorina; Mollie Jurewicz; Andrea Augello; Andrea Vergani; Shirine Dada; Stefano La Rosa; Martin Selig; Jonathan Godwin; Kenneth Law; Claudia Placidi; R Neal Smith; Carlo Capella; Scott Rodig; Chaker N Adra; Mark Atkinson; Mohamed H Sayegh; Reza Abdi
Journal:  J Immunol       Date:  2009-06-26       Impact factor: 5.422

2.  Bone marrow mesenchymal stem cells can be mobilized into peripheral blood by G-CSF in vivo and integrate into traumatically injured cerebral tissue.

Authors:  Jun Deng; Zhong-min Zou; Tao-li Zhou; Yong-ping Su; Guo-ping Ai; Jun-ping Wang; Hui Xu; Shi-wu Dong
Journal:  Neurol Sci       Date:  2011-06-16       Impact factor: 3.307

Review 3.  Human bone marrow mesenchymal stromal/stem cells: current clinical applications and potential for hematology.

Authors:  Yasuo Miura
Journal:  Int J Hematol       Date:  2015-12-21       Impact factor: 2.490

4.  Mesenchymal progenitor cells derived from traumatized muscle enhance neurite growth.

Authors:  Wesley M Jackson; Peter G Alexander; Jamie D Bulken-Hoover; Jared A Vogler; Youngmi Ji; Patricia McKay; Leon J Nesti; Rocky S Tuan
Journal:  J Tissue Eng Regen Med       Date:  2012-05-03       Impact factor: 3.963

Review 5.  Stem cell-derived islet cells for transplantation.

Authors:  Juan Domínguez-Bendala; Luca Inverardi; Camillo Ricordi
Journal:  Curr Opin Organ Transplant       Date:  2011-02       Impact factor: 2.640

6.  The modulation of Th2 immune pathway in the immunosuppressive effect of human umbilical cord mesenchymal stem cells in a murine asthmatic model.

Authors:  Chin-Kan Chan; Ting-Chun Lin; Yung-An Huang; Ya-Shan Chen; Chia-Ling Wu; Huei-Yu Lo; Ming-Ling Kuo; Kang-Hsi Wu; Jing-Long Huang
Journal:  Inflamm Res       Date:  2016-07-06       Impact factor: 4.575

7.  Lung resident mesenchymal stem cells isolated from human lung allografts inhibit T cell proliferation via a soluble mediator.

Authors:  Lamis Jarvinen; Linda Badri; Scott Wettlaufer; Takashi Ohtsuka; Theodore J Standiford; Galen B Toews; David J Pinsky; Marc Peters-Golden; Vibha N Lama
Journal:  J Immunol       Date:  2008-09-15       Impact factor: 5.422

8.  The allogeneic umbilical cord mesenchymal stem cells regulate the function of T helper 17 cells from patients with rheumatoid arthritis in an in vitro co-culture system.

Authors:  Qin Wang; Xiaofeng Li; Jing Luo; Li Zhang; Lihui Ma; Zhiqin Lv; Lijin Xue
Journal:  BMC Musculoskelet Disord       Date:  2012-12-13       Impact factor: 2.362

9.  Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy.

Authors:  Chun-yu Li; Xiao-yun Wu; Jia-bei Tong; Xin-xin Yang; Jing-li Zhao; Quan-fu Zheng; Guo-bin Zhao; Zhi-jie Ma
Journal:  Stem Cell Res Ther       Date:  2015-04-13       Impact factor: 6.832

Review 10.  The immune boundaries for stem cell based therapies: problems and prospective solutions.

Authors:  Abdelkrim Hmadcha; Hmadcha Abdelkrim; Juan Domínguez-Bendala; Domínguez-Bendala Juan; Jane Wakeman; Wakeman Jane; Mohamed Arredouani; Arredouani Mohamed; Bernat Soria; Soria Bernat
Journal:  J Cell Mol Med       Date:  2009-07-06       Impact factor: 5.310
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.