Literature DB >> 15121408

Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells.

Katarina Le Blanc1, Ida Rasmusson, Berit Sundberg, Cecilia Götherström, Moustapha Hassan, Mehmet Uzunel, Olle Ringdén.   

Abstract

Adult bone-marrow-derived mesenchymal stem cells are immunosuppressive and prolong the rejection of mismatched skin grafts in animals. We transplanted haploidentical mesenchymal stem cells in a patient with severe treatment-resistant grade IV acute graft-versus-host disease of the gut and liver. Clinical response was striking. The patient is now well after 1 year. We postulate that mesenchymal stem cells have a potent immunosuppressive effect in vivo.

Entities:  

Mesh：

Year:  2004        PMID： 15121408     DOI： 10.1016/S0140-6736(04)16104-7

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  827 in total

1.  Human AB serum for generation of mesenchymal stem cells from human chorionic villi: comparison with other source and other media including platelet lysate.

Authors:  A Poloni; G Maurizi; F Serrani; S Mancini; G Discepoli; A L Tranquilli; R Bencivenga; P Leoni
Journal:  Cell Prolif       Date:  2011-12-14       Impact factor: 6.831

2.  Human embryonic stem cell-derived mesenchymal stromal cells.

Authors:  Peiman Hematti
Journal:  Transfusion       Date:  2011-11       Impact factor: 3.157

Review 3.  Low-level laser therapy: a useful technique for enhancing the proliferation of various cultured cells.

Authors:  Khalid M AlGhamdi; Ashok Kumar; Noura A Moussa
Journal:  Lasers Med Sci       Date:  2011-01-28       Impact factor: 3.161

4.  Multipotent Mesenchymal Stromal Cells for Autoimmune Diseases.

Authors:  Alan Tyndall
Journal:  Transfus Med Hemother       Date:  2008-07-17       Impact factor: 3.747

5.  Homing of Mesenchymal Stem Cells.

Authors:  Reinhard Henschler; Erika Deak; Erhard Seifried
Journal:  Transfus Med Hemother       Date:  2008-07-21       Impact factor: 3.747

6.  Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors.

Authors:  Dawei Liu; Xiaoxing Kou; Chider Chen; Shiyu Liu; Yao Liu; Wenjing Yu; Tingting Yu; Ruili Yang; Runci Wang; Yanheng Zhou; Songtao Shi
Journal:  Cell Res       Date:  2018-07-20       Impact factor: 25.617

7.  Intranasal delivery of central nervous system-retargeted human mesenchymal stromal cells prolongs treatment efficacy of experimental autoimmune encephalomyelitis.

Authors:  Moa Fransson; Elena Piras; Hao Wang; Joachim Burman; Ida Duprez; Robert A Harris; Katarina LeBlanc; Peetra U Magnusson; Eva Brittebo; Angelica S I Loskog
Journal:  Immunology       Date:  2014-07       Impact factor: 7.397

8.  Distinct Immunoregulatory Mechanisms in Mesenchymal Stem Cells: Role of the Cytokine Environment.

Authors:  Vladimir Holan; Barbora Hermankova; Pavla Bohacova; Jan Kossl; Milada Chudickova; Michaela Hajkova; Magdalena Krulova; Alena Zajicova; Eliska Javorkova
Journal:  Stem Cell Rev Rep       Date:  2016-12       Impact factor: 5.739

9.  Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro.

Authors:  Lauren V Schnabel; Christian M Abratte; John C Schimenti; M Julia Bevilaqua Felippe; Jennifer M Cassano; Teresa L Southard; Jessica A Cross; Lisa A Fortier
Journal:  Regen Med       Date:  2014-04-28       Impact factor: 3.806

Review 10.  Immune regulatory cell infusion for graft-versus-host disease prevention and therapy.

Authors:  Bruce R Blazar; Kelli P A MacDonald; Geoffrey R Hill
Journal:  Blood       Date:  2018-05-04       Impact factor: 22.113
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.