Literature DB >> 17671663

Quantitative PCR analysis of molds in the dust from homes of asthmatic children in North Carolina.

Stephen Vesper1, Craig McKinstry, Peter Ashley, Richard Haugland, Karin Yeatts, Karen Bradham, Erik Svendsen.   

Abstract

The vacuum bag (VB) dust from the homes of 19 asthmatic children in North Carolina (NC) was analyzed by mold specific quantitative PCR. These results were compared to the analysis of the VB dust from 176 homes in the HUD, American Healthy Home Survey of homes in the US. The Environmental Relative Moldiness Index (ERMI) was calculated for each of the homes. The mean and standard deviation (SD) of the ERMI values in the homes of the NC asthmatic children was 16.4 (6.77), compared to the HUD survey VB ERMI value mean and SD of 11.2 (6.72), and was significantly greater (t-test, p = 0.003) in the NC asthmatic children's homes. The molds Chaetomium globosum, Aspergillus fumigatus, and the Eurotium Group were the primary species in the NC homes of asthmatics, making the ERMI values significantly higher (p < 0.02 for each). Vacuum bag dust analysis may be a useful method for estimating the mold burden in a home.

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Year:  2007        PMID: 17671663     DOI: 10.1039/b704359g

Source DB:  PubMed          Journal:  J Environ Monit        ISSN: 1464-0325


  11 in total

1.  Diversity and taxonomy of Chaetomium and chaetomium-like fungi from indoor environments.

Authors:  X W Wang; J Houbraken; J Z Groenewald; M Meijer; B Andersen; K F Nielsen; P W Crous; R A Samson
Journal:  Stud Mycol       Date:  2016-12-08       Impact factor: 16.097

2.  Higher environmental relative moldiness index values measured in homes of adults with asthma, rhinitis, or both conditions.

Authors:  Paul D Blanc; Patricia J Quinlan; Patricia P Katz; John R Balmes; Laura Trupin; Miriam G Cisternas; Larry Wymer; Stephen J Vesper
Journal:  Environ Res       Date:  2013-02-16       Impact factor: 6.498

3.  Production and characterization of IgM monoclonal antibodies against hyphal antigens of Stachybotrys species.

Authors:  Ajay P Nayak; Brett J Green; Erika Janotka; Francoise M Blachere; Stephen J Vesper; Donald H Beezhold; Detlef Schmechel
Journal:  Hybridoma (Larchmt)       Date:  2011-02

4.  Infant origins of childhood asthma associated with specific molds.

Authors:  Tiina Reponen; James Lockey; David I Bernstein; Stephen J Vesper; Linda Levin; Gurjit K Khurana Hershey; Shu Zheng; Patrick Ryan; Sergey A Grinshpun; Manuel Villareal; Grace Lemasters
Journal:  J Allergy Clin Immunol       Date:  2012-07-11       Impact factor: 10.793

5.  Production of a Chaetomium globosum enolase monoclonal antibody.

Authors:  Brett J Green; Ajay P Nayak; Angela R Lemons; William R Rittenour; Justin M Hettick; Donald H Beezhold
Journal:  Monoclon Antib Immunodiagn Immunother       Date:  2014-12

6.  Phylogenetic reassessment of the Chaetomium globosum species complex.

Authors:  X W Wang; L Lombard; J Z Groenewald; J Li; S I R Videira; R A Samson; X Z Liu; P W Crous
Journal:  Persoonia       Date:  2015-09-25       Impact factor: 11.051

Review 7.  Emerging Insights into the Occupational Mycobiome.

Authors:  Brett J Green
Journal:  Curr Allergy Asthma Rep       Date:  2018-09-27       Impact factor: 4.806

8.  Higher Environmental Relative Moldiness Index (ERMI) values measured in homes of asthmatic children in Boston, Kansas City, and San Diego.

Authors:  Stephen Vesper; Charles Barnes; Christina E Ciaccio; Alan Johanns; Kevin Kennedy; Johnna S Murphy; Arcela Nunez-Alvarez; Megan T Sandel; David Cox; Gary Dewalt; Peter J Ashley
Journal:  J Asthma       Date:  2012-11-09       Impact factor: 2.515

Review 9.  Respiratory and allergic health effects of dampness, mold, and dampness-related agents: a review of the epidemiologic evidence.

Authors:  Mark J Mendell; Anna G Mirer; Kerry Cheung; My Tong; Jeroen Douwes
Journal:  Environ Health Perspect       Date:  2011-01-26       Impact factor: 9.031

10.  Dampness, indoor mould, fungal DNA and respiratory health - molecular methods in indoor epidemiology.

Authors:  D Norbäck; G-H Cai
Journal:  Clin Exp Allergy       Date:  2015-05       Impact factor: 5.018

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