| Literature DB >> 17671640 |
George A Calin1, Carlo M Croce.
Abstract
There is widespread aberrant expression of mature and/or precursor microRNAs in cancer cells, as microRNAs are deregulated consequent to chromosomal alterations and other genomic abnormalities. The identification of such abnormalities has a clear diagnostic and prognostic significance, and there are ever increasing examples of links between certain human cancers and modifications at microRNA loci.Entities:
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Year: 2007 PMID: 17671640 PMCID: PMC1934569 DOI: 10.1172/JCI32577
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808