Literature DB >> 17671447

Pharmacoproteomics: advancing the efficacy and safety of regenerative therapeutics.

D K Arrell1, N J Niederländer, C Perez-Terzic, S Chung, A Behfar, A Terzic.   

Abstract

Proteomic analyses encompass a suite of high-throughput technologies for large-scale separation and identification of proteins responsible for execution of physiological processes. As such, proteomics is ideally suited to dissecting developmental complexity and dynamics, an understanding of which is vital to the realization of regenerative therapeutic medicine. Pharmacoproteomics is increasingly targeting characterization of regenerative therapeutic strategies. A perspective on the application of proteomics to further our understanding of cardiac regenerative medicine, in concert with guided cardiogenic programming, is delineated herein.

Mesh:

Year:  2007        PMID: 17671447     DOI: 10.1038/sj.clpt.6100310

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  13 in total

1.  ATP-sensitive K(+) channel-deficient dilated cardiomyopathy proteome remodeled by embryonic stem cell therapy.

Authors:  Jelena Zlatkovic-Lindor; D Kent Arrell; Satsuki Yamada; Timothy J Nelson; Andre Terzic
Journal:  Stem Cells       Date:  2010-08       Impact factor: 6.277

2.  A reagent to facilitate protein recovery from cells and tissues.

Authors:  Byeong Hee Hwang; Nishit Doshi; Kenneth Y Tsai; Samir Mitragotri
Journal:  Drug Deliv Transl Res       Date:  2012-10       Impact factor: 4.617

3.  Optimized lysis buffer reagents for solubilization and preservation of proteins from cells and tissues.

Authors:  Byeong Hee Hwang; Kenneth Y Tsai; Samir Mitragotri
Journal:  Drug Deliv Transl Res       Date:  2013-10       Impact factor: 4.617

4.  Developmental restructuring of the creatine kinase system integrates mitochondrial energetics with stem cell cardiogenesis.

Authors:  Susan Chung; Petras P Dzeja; Randolph S Faustino; Andre Terzic
Journal:  Ann N Y Acad Sci       Date:  2008-12       Impact factor: 5.691

5.  Embryonic stem cell therapy of heart failure in genetic cardiomyopathy.

Authors:  Satsuki Yamada; Timothy J Nelson; Ruben J Crespo-Diaz; Carmen Perez-Terzic; Xiao-Ke Liu; Takashi Miki; Susumu Seino; Atta Behfar; Andre Terzic
Journal:  Stem Cells       Date:  2008-07-31       Impact factor: 6.277

6.  Cardiogenic induction of pluripotent stem cells streamlined through a conserved SDF-1/VEGF/BMP2 integrated network.

Authors:  Anca Chiriac; Timothy J Nelson; Randolph S Faustino; Atta Behfar; Andre Terzic
Journal:  PLoS One       Date:  2010-04-01       Impact factor: 3.240

7.  Bioinformatic primer for clinical and translational science.

Authors:  Randolph S Faustino; Anca Chiriac; Andre Terzic
Journal:  Clin Transl Sci       Date:  2008-09       Impact factor: 4.689

8.  Strategies for therapeutic repair: The "R(3)" regenerative medicine paradigm.

Authors:  Timothy J Nelson; Atta Behfar; Andre Terzic
Journal:  Clin Transl Sci       Date:  2008-09       Impact factor: 4.689

Review 9.  Systems-based technologies in profiling the stem cell molecular framework for cardioregenerative medicine.

Authors:  Saranya P Wyles; Randolph S Faustino; Xing Li; Andre Terzic; Timothy J Nelson
Journal:  Stem Cell Rev Rep       Date:  2015-06       Impact factor: 5.739

Review 10.  Guided stem cell cardiopoiesis: discovery and translation.

Authors:  Atta Behfar; Randolph S Faustino; D Kent Arrell; Petras P Dzeja; Carmen Perez-Terzic; Andre Terzic
Journal:  J Mol Cell Cardiol       Date:  2008-09-26       Impact factor: 5.000

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