OBJECTIVE: To investigate the clinical features of hyperemesis gravidarum in Eastern Asian women. METHOD: Retrospective cohort study was conducted based on delivery records. Hyperemesis gravidarum was defined as a pregnancy with severe nausea and vomiting necessitating hospitalization with a body weight loss of over 5% from pre-pregnancy weight with ketonuria. The onset is at 10 weeks of gestation or less. Maternal and neonatal variables were compared. RESULT: There were 3,350 singleton deliveries in the study period. All subjects were Eastern Asian women. Hyperemesis gravidarum was observed in 119 cases (3.6%). Hyperemesis gravidarum subjects had a smaller pre-pregnancy body weight (50.5 +/- 0.64 kg vs. 51.8 +/- 0.16 kg, p = 0.046) and a smaller pre-pregnancy body mass index compared to non-hyperemetic subjects (20.2 +/- 0.21 kg/m2 vs. 20.8 +/- 0.06 kg/m2, p = 0.02). CONCLUSION: The Eastern Asian population had a significantly higher incidence of hyperemesis gravidarum. Small pre-pregnancy body habitus increased the risk of hyperemesis gravidarum. 2007 S. Karger AG, Basel
OBJECTIVE: To investigate the clinical features of hyperemesis gravidarum in Eastern Asian women. METHOD: Retrospective cohort study was conducted based on delivery records. Hyperemesis gravidarum was defined as a pregnancy with severe nausea and vomiting necessitating hospitalization with a body weight loss of over 5% from pre-pregnancy weight with ketonuria. The onset is at 10 weeks of gestation or less. Maternal and neonatal variables were compared. RESULT: There were 3,350 singleton deliveries in the study period. All subjects were Eastern Asian women. Hyperemesis gravidarum was observed in 119 cases (3.6%). Hyperemesis gravidarum subjects had a smaller pre-pregnancy body weight (50.5 +/- 0.64 kg vs. 51.8 +/- 0.16 kg, p = 0.046) and a smaller pre-pregnancy body mass index compared to non-hyperemetic subjects (20.2 +/- 0.21 kg/m2 vs. 20.8 +/- 0.06 kg/m2, p = 0.02). CONCLUSION: The Eastern Asian population had a significantly higher incidence of hyperemesis gravidarum. Small pre-pregnancy body habitus increased the risk of hyperemesis gravidarum. 2007 S. Karger AG, Basel
Authors: Yafeng Zhang; Rita M Cantor; Kimber MacGibbon; Roberto Romero; Thomas M Goodwin; Patrick M Mullin; Marlena S Fejzo Journal: Am J Obstet Gynecol Date: 2010-10-25 Impact factor: 8.661
Authors: Heleen M Koudijs; Ary I Savitri; Joyce L Browne; Dwirani Amelia; Mohammad Baharuddin; Diederick E Grobbee; Cuno S P M Uiterwaal Journal: BMC Pregnancy Childbirth Date: 2016-11-25 Impact factor: 3.007