Literature DB >> 17662552

In vitro antibacterial activities of tigecycline and comparative agents by time-kill kinetic studies in fresh Mueller-Hinton broth.

Peter J Petersen1, C Hal Jones, Patricia A Bradford.   

Abstract

Time-kill kinetics performed with tigecycline, in fresh MHB, demonstrated a consistent 1 to 2 log(10) CFU/ml reduction in bacterial counts against the majority of clinically relevant pathogens tested. Although classified as a bacteriostatic agent, tigecycline shows bactericidal activity against select isolates associated with serious infection. In general, vancomycin and imipenem demonstrated bactericidal activity.

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Year:  2007        PMID： 17662552     DOI： 10.1016/j.diagmicrobio.2007.05.013

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  13 in total

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2.  Antibacterial Activity and Mode of Action of a Sulfonamide-Based Class of Oxaborole Leucyl-tRNA-Synthetase Inhibitors.

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Review 4.  Tigecycline: in community-acquired pneumonia.

Authors:  Kate McKeage; Gillian M Keating
Journal:  Drugs       Date:  2008       Impact factor: 9.546

Review 5.  Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

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Authors:  Helen Giamarellou; Garyphallia Poulakou
Journal:  Drugs       Date:  2009-10-01       Impact factor: 9.546

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Journal:  Antibiotics (Basel)       Date:  2022-04-13

9.  Prenylated Flavonoids with Potential Antimicrobial Activity: Synthesis, Biological Activity, and In Silico Study.

Authors:  Mauricio Osorio; Marcela Carvajal; Alejandra Vergara; Estefania Butassi; Susana Zacchino; Carolina Mascayano; Margarita Montoya; Sophia Mejías; Marcelo Cortez-San Martín; Yesseny Vásquez-Martínez
Journal:  Int J Mol Sci       Date:  2021-05-22       Impact factor: 5.923

10.  Novel vancomycin-peptide conjugate as potent antibacterial agent against vancomycin-resistant Staphylococcus aureus.

Authors:  Pavlina Jelinkova; Zbynek Splichal; Ana Maria Jimenez Jimenez; Yazan Haddad; Aninda Mazumdar; Vishma Pratap Sur; Vedran Milosavljevic; Pavel Kopel; Hana Buchtelova; Roman Guran; Ondrej Zitka; Lukas Richtera; Dagmar Hegerova; Zbynek Heger; Amitava Moulick; Vojtech Adam
Journal:  Infect Drug Resist       Date:  2018-10-12       Impact factor: 4.003
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