PURPOSE: To determine optic disc size and its associations in an adult population in central India. METHODS: The Central India Eye and Medical Study (CIEMS), Part 1 is a population-based, cross-sectional cohort study and included 1000 subjects out of 1314 (76.1%) subjects from a rural area of Maharasthra/India, aged 30+ years, invited to participate. Confocal laser scanning tomographic optic disc images were morphometrically examined. RESULTS: Mean optic disc area (2.25 +/- 0.51 mm2, range 1.12-4.61 mm2) was significantly correlated with myopic refractive error (p < 0.001) and axial length (p < 0.001), whereas gender (p = 0.14), body height (p = 0.44) and best corrected visual acuity (p = 0.59) were not significantly associated in multiple regression analysis. CONCLUSIONS: Mean optic disc area is larger in the central Indian population than in White people. Axial length and myopic refractive error are independent factors that influence optic disc size.
PURPOSE: To determine optic disc size and its associations in an adult population in central India. METHODS: The Central India Eye and Medical Study (CIEMS), Part 1 is a population-based, cross-sectional cohort study and included 1000 subjects out of 1314 (76.1%) subjects from a rural area of Maharasthra/India, aged 30+ years, invited to participate. Confocal laser scanning tomographic optic disc images were morphometrically examined. RESULTS: Mean optic disc area (2.25 +/- 0.51 mm2, range 1.12-4.61 mm2) was significantly correlated with myopic refractive error (p < 0.001) and axial length (p < 0.001), whereas gender (p = 0.14), body height (p = 0.44) and best corrected visual acuity (p = 0.59) were not significantly associated in multiple regression analysis. CONCLUSIONS: Mean optic disc area is larger in the central Indian population than in White people. Axial length and myopic refractive error are independent factors that influence optic disc size.
Authors: Wishal D Ramdas; Leonieke M E van Koolwijk; M Kamran Ikram; Nomdo M Jansonius; Paulus T V M de Jong; Arthur A B Bergen; Aaron Isaacs; Najaf Amin; Yurii S Aulchenko; Roger C W Wolfs; Albert Hofman; Fernando Rivadeneira; Ben A Oostra; Andre G Uitterlinden; Pirro Hysi; Christopher J Hammond; Hans G Lemij; Johannes R Vingerling; Caroline C W Klaver; Cornelia M van Duijn Journal: PLoS Genet Date: 2010-06-10 Impact factor: 5.917
Authors: Anthony P Khawaja; Michelle P Y Chan; David C Broadway; David F Garway-Heath; Robert Luben; Jennifer L Y Yip; Shabina Hayat; Kay-Tee Khaw; Paul J Foster Journal: Invest Ophthalmol Vis Sci Date: 2013-10-09 Impact factor: 4.799