Literature DB >> 17660545

Caenorhabditis elegans SDF-9 enhances insulin/insulin-like signaling through interaction with DAF-2.

Victor L Jensen1, Patrice S Albert, Donald L Riddle.   

Abstract

SDF-9 is a modulator of Caenorhabditis elegans insulin/IGF-1 signaling that may interact directly with the DAF-2 receptor. SDF-9 is a tyrosine phosphatase-like protein that, when mutated, enhances many partial loss-of-function mutants in the dauer pathway except for the temperature-sensitive mutant daf-2(m41). We propose that SDF-9 stabilizes the active phosphorylated state of DAF-2 or acts as an adaptor protein to enhance insulin-like signaling.

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Year:  2007        PMID： 17660545      PMCID： PMC2013707          DOI： 10.1534/genetics.107.076703

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  38 in total

1.  Dauer formation induced by high temperatures in Caenorhabditis elegans.

Authors:  M Ailion; J H Thomas
Journal:  Genetics       Date:  2000-11       Impact factor: 4.562

2.  A gene expression map for Caenorhabditis elegans.

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Authors:  D A Birnby; E M Link; J J Vowels; H Tian; P L Colacurcio; J H Thomas
Journal:  Genetics       Date:  2000-05       Impact factor: 4.562

5.  Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9.

Authors:  R Firestein; X Cui; P Huie; M L Cleary
Journal:  Mol Cell Biol       Date:  2000-07       Impact factor: 4.272

Review 6.  Cancer, type 2 diabetes, and ageing: news from flies and worms.

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Journal:  Swiss Med Wkly       Date:  2004-12-18       Impact factor: 2.193

Review 7.  Alterations in components of the TGF-beta superfamily signaling pathways in human cancer.

Authors:  Laurence Levy; Caroline S Hill
Journal:  Cytokine Growth Factor Rev       Date:  2005-11-23       Impact factor: 7.638

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Authors:  Jennifer Macdonald; Zhengzhe Li; Wanwen Su; Linda J Pike
Journal:  Biochim Biophys Acta       Date:  2006-05-13

9.  Small-molecule pheromones that control dauer development in Caenorhabditis elegans.

Authors:  Rebecca A Butcher; Masaki Fujita; Frank C Schroeder; Jon Clardy
Journal:  Nat Chem Biol       Date:  2007-06-10       Impact factor: 15.040

10.  Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.

Authors:  Patrick J Hu; Jinling Xu; Gary Ruvkun
Journal:  PLoS Genet       Date:  2006-05-18       Impact factor: 5.917
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Authors:  Victor L Jensen; Karina T Simonsen; Yu-Hui Lee; Donha Park; Donald L Riddle
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4.  Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans.

Authors:  Donha Park; Karen L Jones; Hyojin Lee; Terrance P Snutch; Stefan Taubert; Donald L Riddle
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5.  TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans.

Authors:  Annabel A Ferguson; Sudipa Roy; Kaitlyn N Kormanik; Yongsoon Kim; Kathleen J Dumas; Vladimir B Ritov; Dietrich Matern; Patrick J Hu; Alfred L Fisher
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6.  Polymorphic segmental duplication in the nematode Caenorhabditis elegans.

Authors:  Ismael A Vergara; Allan K Mah; Jim C Huang; Maja Tarailo-Graovac; Robert C Johnsen; David L Baillie; Nansheng Chen
Journal:  BMC Genomics       Date:  2009-07-21       Impact factor: 3.969

7.  The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans.

Authors:  Annette O Estevez; Kathleen L Morgan; Nathaniel J Szewczyk; David Gems; Miguel Estevez
Journal:  Neurotoxicology       Date:  2014-01-06       Impact factor: 4.294
  7 in total

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