Literature DB >> 11557892

A gene expression map for Caenorhabditis elegans.

S K Kim1, J Lund, M Kiraly, K Duke, M Jiang, J M Stuart, A Eizinger, B N Wylie, G S Davidson.   

Abstract

We have assembled data from Caenorhabditis elegans DNA microarray experiments involving many growth conditions, developmental stages, and varieties of mutants. Co-regulated genes were grouped together and visualized in a three-dimensional expression map that displays correlations of gene expression profiles as distances in two dimensions and gene density in the third dimension. The gene expression map can be used as a gene discovery tool to identify genes that are co-regulated with known sets of genes (such as heat shock, growth control genes, germ line genes, and so forth) or to uncover previously unknown genetic functions (such as genomic instability in males and sperm caused by specific transposons).

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Year:  2001        PMID: 11557892     DOI: 10.1126/science.1061603

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  238 in total

1.  Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity.

Authors:  Tetsuya S Tanaka; Tilo Kunath; Wendy L Kimber; Saied A Jaradat; Carole A Stagg; Masayuki Usuda; Takashi Yokota; Hitoshi Niwa; Janet Rossant; Minoru S H Ko
Journal:  Genome Res       Date:  2002-12       Impact factor: 9.043

2.  Visible trends in functional genomics.

Authors:  Anders Blomberg; Per Sunnerhagen
Journal:  Funct Integr Genomics       Date:  2003-05-13       Impact factor: 3.410

Review 3.  High throughput gene expression profiling: a molecular approach to integrative physiology.

Authors:  Mingyu Liang; Allen W Cowley; Andrew S Greene
Journal:  J Physiol       Date:  2004-01-01       Impact factor: 5.182

4.  RNAiDB and PhenoBlast: web tools for genome-wide phenotypic mapping projects.

Authors:  Kristin C Gunsalus; Wan-Chen Yueh; Philip MacMenamin; Fabio Piano
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

5.  Subsystem identification through dimensionality reduction of large-scale gene expression data.

Authors:  Philip M Kim; Bruce Tidor
Journal:  Genome Res       Date:  2003-07       Impact factor: 9.043

6.  Asymmetric sequence divergence of duplicate genes.

Authors:  Gavin C Conant; Andreas Wagner
Journal:  Genome Res       Date:  2003-09       Impact factor: 9.043

7.  A gene recommender algorithm to identify coexpressed genes in C. elegans.

Authors:  Art B Owen; Josh Stuart; Kathy Mach; Anne M Villeneuve; Stuart Kim
Journal:  Genome Res       Date:  2003-08       Impact factor: 9.043

8.  WormBase: a multi-species resource for nematode biology and genomics.

Authors:  Todd W Harris; Nansheng Chen; Fiona Cunningham; Marcela Tello-Ruiz; Igor Antoshechkin; Carol Bastiani; Tamberlyn Bieri; Darin Blasiar; Keith Bradnam; Juancarlos Chan; Chao-Kung Chen; Wen J Chen; Paul Davis; Eimear Kenny; Ranjana Kishore; Daniel Lawson; Raymond Lee; Hans-Michael Muller; Cecilia Nakamura; Philip Ozersky; Andrei Petcherski; Anthony Rogers; Aniko Sabo; Erich M Schwarz; Kimberly Van Auken; Qinghua Wang; Richard Durbin; John Spieth; Paul W Sternberg; Lincoln D Stein
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

9.  A first version of the Caenorhabditis elegans Promoterome.

Authors:  Denis Dupuy; Qian-Ru Li; Bart Deplancke; Mike Boxem; Tong Hao; Philippe Lamesch; Reynaldo Sequerra; Stephanie Bosak; Lynn Doucette-Stamm; Ian A Hope; David E Hill; Albertha J M Walhout; Marc Vidal
Journal:  Genome Res       Date:  2004-10       Impact factor: 9.043

10.  RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans.

Authors:  Alla Grishok; Sebastian Hoersch; Phillip A Sharp
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-10       Impact factor: 11.205

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