Literature DB >> 17655054

Peroxidation of subcellular organelles: formation of lipofuscinlike fluorescent pigments.

K S Chio1, U Reiss, B Fletcher, A L Tappel.   

Abstract

Lipid peroxidation of subcellular organelles gives fluorescent products which have fluorescence and excitation spectra similar to those of lipofuscin pigments. Fluorescence and excitation spectra and total fluorescence in the 460-nanometer region are useful for qualitative identification and quantitative measurement of the Schiff base product, a molecular damage site of lipid peroxidation which develops during some aging processes.

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Year:  1969        PMID： 17655054     DOI： 10.1126/science.166.3912.1535

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  35 in total

1.  Fractionation and analysis of fluorescent products of lipid peroxidation.

Authors:  R Trombly; A Tappel
Journal:  Lipids       Date:  1975-08       Impact factor: 1.880

2.  Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments.

Authors:  Jiří Wilhelm; Joško Ivica; Dmytro Kagan; Petr Svoboda
Journal:  Mol Cell Biochem       Date:  2010-10-19       Impact factor: 3.396

3.  Kinetics of formation of fluorescent products from hexanal and L-lysine in a two-phase system.

Authors:  H Stapelfeldt; L H Skibsted
Journal:  Lipids       Date:  1996-11       Impact factor: 1.880

4.  Studies on chemical nature of lipofusion (age pigment) isolated from normal human brain.

Authors:  R D Taubold
Journal:  Lipids       Date:  1975-07       Impact factor: 1.880

Review 5.  Mechanisms of oxidant-induced changes in erythrocytes.

Authors:  J R Hatherill; G O Till; P A Ward
Journal:  Agents Actions       Date:  1991-03

6.  Studies of the fluorescent products of lipid oxidation in aqueous emulsion with glycine and on the surface of silica gel.

Authors:  H Shimasaki; O S Privett; I Hara
Journal:  J Am Oil Chem Soc       Date:  1977-03       Impact factor: 1.849

7.  Muscle lipofuscin content and satellite cell volume is increased after high altitude exposure in humans.

Authors:  M Martinelli; R Winterhalder; P Cerretelli; H Howald; H Hoppeler
Journal:  Experientia       Date:  1990-07-15

8.  The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthase.

Authors:  I M Fearnley; J E Walker; R D Martinus; R D Jolly; K B Kirkland; G J Shaw; D N Palmer
Journal:  Biochem J       Date:  1990-06-15       Impact factor: 3.857

9.  Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

Authors:  J Schuh; G F Fairclough; R H Haschemeyer
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

10.  Fluorescent substances derived from the reaction of 13-monohydroperoxylinoleic acid and methylamine.

Authors:  K Kikugawa; S Watanabe
Journal:  Lipids       Date:  1988-04       Impact factor: 1.880
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