Literature DB >> 17654285

A new cytotoxic carbazole alkaloid from Clausena excavata.

Y H Taufiq-Yap1, T H Peh, G C L Ee, M Rahmani, M A Sukari, A M Ali, R Muse.   

Abstract

A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1), together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line.

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Year:  2007        PMID: 17654285     DOI: 10.1080/14786410701258875

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  3 in total

1.  Antiproliferative Properties of Clausine-B against Cancer Cell Lines.

Authors:  Wan Nor I'zzah Wan Mohd Zain; Asmah Rahmat; Fauziah Othman; Taufiq Yun Hin Yap
Journal:  Malays J Med Sci       Date:  2009-07

2.  Bio-Guided Isolation of Prospective Bioactive Constituents from Roots of Clausena indica (Dalzell) Oliv.

Authors:  Nguyen Van Quan; Tran Dang Xuan; La Hoang Anh; Hoang-Dung Tran
Journal:  Molecules       Date:  2019-12-04       Impact factor: 4.411

3.  Anti-Enterococcus Faecalis, Cytotoxicity, Phytotoxicity, and Anticancer Studies on Clausena excavata Burum. f. (Rutaceae) Leaves.

Authors:  Shaymaa Fadhel Abbas Albaayit; Rukesh Maharjan; Rasedee Abdullah; Mohd Hezmee Mohd Noor
Journal:  Biomed Res Int       Date:  2021-02-23       Impact factor: 3.411

  3 in total

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