Literature DB >> 17653413

[Evolution of CD4+ T-cell count among AIDS patients in socially unequal contexts].

Maria Aparecida de Assis Patroclo1, Roberto de Andrade Medronho.   

Abstract

This study analyzed the evolution in CD4+ T-cell count in AIDS patients in the city of Rio de Janeiro, Brazil, who were on highly active antiretroviral treatment (HAART) at the Municipal Health Centers in the Maré neighborhood, located in a large slum area, and in Copacabana, located in the city's more affluent South Side. Immediately prior to HAART, the median CD4+ T-lymphocyte count was 181 cells/mm(3) in Maré and 182 cells/mm(3) in Copacabana. After 24 weeks of HAART, the median count reached 302 and 315/mm3 in the two health centers, respectively. Following HAART, individuals with AIDS in Maré had 2.8 times the odds of not presenting an immune response as compared to cases in Copacabana (95%CI: 1.1-7.2). Slum residents from Maré had 3.7 the odds of not presenting an immune response as compared to slum residents from Copacabana (95%CI: 1.2-11.5). Males from Maré had 4.4 the odds of not presenting an immune response as compared to those from Copacabana (95%CI: 1.1-18.2). The results suggest a worse prognosis and higher case-fatality for AIDS patients from slums, independently of access to HAART.

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Year:  2007        PMID: 17653413     DOI: 10.1590/s0102-311x2007000800022

Source DB:  PubMed          Journal:  Cad Saude Publica        ISSN: 0102-311X            Impact factor:   1.632


  2 in total

1.  Factors related to changes in CD4+ T-cell counts over time in patients living with HIV/AIDS: a multilevel analysis.

Authors:  Ulisses Ramos Montarroyos; Demócrito Barros Miranda-Filho; Cibele Comini César; Wayner Vieira Souza; Heloisa Ramos Lacerda; Maria de Fátima Pessoa Militão Albuquerque; Mariana Freitas Aguiar; Ricardo Arraes de Alencar Ximenes
Journal:  PLoS One       Date:  2014-02-05       Impact factor: 3.240

2.  HIV testing and clinical status upon admission to a specialized health care unit in Pará, Brazil.

Authors:  Paulo Afonso Martins Abati; Aluisio Cotrim Segurado
Journal:  Rev Saude Publica       Date:  2015-02-27       Impact factor: 2.106

  2 in total

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