Literature DB >> 17644019

Acceptable low-phenylalanine foods and beverages can be made with glycomacropeptide from cheese whey for individuals with PKU.

Kyungwha Lim1, Sandra C van Calcar, Kathryn L Nelson, Sally T Gleason, Denise M Ney.   

Abstract

Glycomacropeptide (GMP) is a whey protein that contains no aromatic amino acids including phenylalanine (phe). The objective of this study was to make a variety of palatable, low-phe foods and beverages with GMP and to assess their acceptability by conducting consumer sensory studies in individuals with PKU. Results demonstrate acceptability of products made with GMP. GMP supplemented with limiting indispensable amino acids could provide an alternative protein source for individuals with PKU.

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Year:  2007        PMID: 17644019      PMCID: PMC2032016          DOI: 10.1016/j.ymgme.2007.06.004

Source DB:  PubMed          Journal:  Mol Genet Metab        ISSN: 1096-7192            Impact factor:   4.797


  6 in total

Review 1.  Biological activities of bovine glycomacropeptide.

Authors:  E P Brody
Journal:  Br J Nutr       Date:  2000-11       Impact factor: 3.718

2.  Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids.

Authors:  Paula Trumbo; Sandra Schlicker; Allison A Yates; Mary Poos
Journal:  J Am Diet Assoc       Date:  2002-11

Review 3.  Manufacture and use of dairy protein fractions.

Authors:  Mark R Etzel
Journal:  J Nutr       Date:  2004-04       Impact factor: 4.798

Review 4.  Phenylketonuria (PKU): screening and management.

Authors: 
Journal:  NIH Consens Statement       Date:  2000 Oct 16-18

5.  Phenylketonuria in adulthood: a collaborative study.

Authors:  R Koch; B Burton; G Hoganson; R Peterson; W Rhead; B Rouse; R Scott; J Wolff; A M Stern; F Guttler; M Nelson; F de la Cruz; J Coldwell; R Erbe; M T Geraghty; C Shear; J Thomas; C Azen
Journal:  J Inherit Metab Dis       Date:  2002-09       Impact factor: 4.982

6.  Necessity of complete intake of phenylalanine-free amino acid mixture for metabolic control of phenylketonuria.

Authors:  G P Duran; F J Rohr; A Slonim; F Güttler; H L Levy
Journal:  J Am Diet Assoc       Date:  1999-12
  6 in total
  20 in total

Review 1.  Phenylketonuria: a 21st century perspective.

Authors:  Francjan J van Spronsen
Journal:  Nat Rev Endocrinol       Date:  2010-09       Impact factor: 43.330

2.  Nutritional status in patients with phenylketonuria using glycomacropeptide as their major protein source.

Authors:  A Pinto; M F Almeida; P C Ramos; S Rocha; A Guimas; R Ribeiro; E Martins; A Bandeira; A MacDonald; J C Rocha
Journal:  Eur J Clin Nutr       Date:  2017-04-12       Impact factor: 4.016

Review 3.  Food products made with glycomacropeptide, a low-phenylalanine whey protein, provide a new alternative to amino Acid-based medical foods for nutrition management of phenylketonuria.

Authors:  Sandra C van Calcar; Denise M Ney
Journal:  J Acad Nutr Diet       Date:  2012-08       Impact factor: 4.910

4.  Glycomacropeptide, a low-phenylalanine protein isolated from cheese whey, supports growth and attenuates metabolic stress in the murine model of phenylketonuria.

Authors:  Patrick Solverson; Sangita G Murali; Adam S Brinkman; David W Nelson; Murray K Clayton; Chi-Liang Eric Yen; Denise M Ney
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-01-31       Impact factor: 4.310

5.  Breakfast with glycomacropeptide compared with amino acids suppresses plasma ghrelin levels in individuals with phenylketonuria.

Authors:  Erin L MacLeod; Murray K Clayton; Sandra C van Calcar; Denise M Ney
Journal:  Mol Genet Metab       Date:  2010-04-14       Impact factor: 4.797

Review 6.  Nutritional management of PKU with glycomacropeptide from cheese whey.

Authors:  D M Ney; S T Gleason; S C van Calcar; E L MacLeod; K L Nelson; M R Etzel; G M Rice; J A Wolff
Journal:  J Inherit Metab Dis       Date:  2008-10-29       Impact factor: 4.982

7.  Improved nutritional management of phenylketonuria by using a diet containing glycomacropeptide compared with amino acids.

Authors:  Sandra C van Calcar; Erin L MacLeod; Sally T Gleason; Mark R Etzel; Murray K Clayton; Jon A Wolff; Denise M Ney
Journal:  Am J Clin Nutr       Date:  2009-02-25       Impact factor: 7.045

8.  Pretreatment with glycomacropeptide reduces allergen sensitization, alleviates immediate cutaneous hypersensitivity and protects from anaphylaxis.

Authors:  M Jiménez; N A Chávez; E Salinas
Journal:  Clin Exp Immunol       Date:  2012-10       Impact factor: 4.330

Review 9.  Phenylketonuria: a review of current and future treatments.

Authors:  Naz Al Hafid; John Christodoulou
Journal:  Transl Pediatr       Date:  2015-10

10.  Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways.

Authors:  Pilar Requena; Abdelali Daddaoua; Emilia Guadix; Antonio Zarzuelo; María Dolores Suárez; Fermín Sánchez de Medina; Olga Martínez-Augustin
Journal:  Br J Pharmacol       Date:  2009-06-22       Impact factor: 8.739

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