Literature DB >> 17636914

Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB.

Matthew B Soellner1, Katherine A Rawls, Christoph Grundner, Tom Alber, Jonathan A Ellman.   

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Year:  2007        PMID： 17636914     DOI： 10.1021/ja0727520

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  29 in total

1.  Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening.

Authors:  Kristoff T Homan; Deepa Balasubramaniam; Adam P R Zabell; Olaf Wiest; Paul Helquist; Cynthia V Stauffacher
Journal:  Bioorg Med Chem       Date:  2010-04-21       Impact factor: 3.641

2.  Theoretical studies on the interaction of biphenyl inhibitors with Mycobacterium tuberculosis protein tyrosine phosphatase MptpB.

Authors:  Lihua Dong; Junyou Shi; Yongjun Liu
Journal:  J Mol Model       Date:  2012-03-11       Impact factor: 1.810

3.  Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.

Authors:  Katherine A Rawls; Christoph Grundner; Jonathan A Ellman
Journal:  Org Biomol Chem       Date:  2010-07-19       Impact factor: 3.876

Review 4.  Using specificity to strategically target proteases.

Authors:  Mark D Lim; Charles S Craik
Journal:  Bioorg Med Chem       Date:  2008-03-30       Impact factor: 3.641

5.  Oxime-based click chemistry in the development of 3-isoxazolecarboxylic acid containing inhibitors of Yersinia pestis protein tyrosine phosphatase, YopH.

Authors:  Medhanit Bahta; Terrence R Burke
Journal:  ChemMedChem       Date:  2011-06-10       Impact factor: 3.466

6.  Fluorogenic structure activity library pinpoints molecular variations in substrate specificity of structurally homologous esterases.

Authors:  Alex White; Andrew Koelper; Arielle Russell; Erik M Larsen; Charles Kim; Luke D Lavis; Geoffrey C Hoops; R Jeremy Johnson
Journal:  J Biol Chem       Date:  2018-07-13       Impact factor: 5.157

7.  Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

Authors:  Katherine A Rawls; P Therese Lang; Jun Takeuchi; Shinichi Imamura; Tyler D Baguley; Christoph Grundner; Tom Alber; Jonathan A Ellman
Journal:  Bioorg Med Chem Lett       Date:  2009-10-25       Impact factor: 2.823

Review 8.  Small molecule tools for functional interrogation of protein tyrosine phosphatases.

Authors:  Rongjun He; Li-Fan Zeng; Yantao He; Sheng Zhang; Zhong-Yin Zhang
Journal:  FEBS J       Date:  2012-08-16       Impact factor: 5.542

9.  Utilization of nitrophenylphosphates and oxime-based ligation for the development of nanomolar affinity inhibitors of the Yersinia pestis outer protein H (YopH) phosphatase.

Authors:  Medhanit Bahta; George T Lountos; Beverly Dyas; Sung-Eun Kim; Robert G Ulrich; David S Waugh; Terrence R Burke
Journal:  J Med Chem       Date:  2011-03-28       Impact factor: 7.446

10.  Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis.

Authors:  Rongjun He; Li-Fan Zeng; Yantao He; Li Wu; Andrea Michelle Gunawan; Zhong-Yin Zhang
Journal:  Chem Commun (Camb)       Date:  2013-03-11       Impact factor: 6.222
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