PURPOSE: The aim of this study was to determine the comparative diagnostic values of late gadolinium-enhanced magnetic resonance imaging (MRI) and first-pass dynamic MRI for predicting functional recovery of regional myocardial contraction in patients early after acute myocardial infarction. MATERIALS AND METHODS: First-pass and late-enhanced MRI were performed in 18 patients 5.5 +/- 2.5 days after the onset of myocardial infarction. Images analysis was performed using a 12-segment model. Regional systolic wall thickening (SWT) was measured on cine-MRI obtained 273 +/- 130 days later. RESULTS: Late-enhanced MRI revealed hyperenhancement in all patients, whereas hypoenhancement on first-pass MRI was observed in 67% (12/18) of the patients. The area under the receiver operating characteristics curve was 0.86 for late-enhanced MRI and 0.74 for first-pass MRI (P = 0.27). First-pass MRI was useful for predicting functional recovery of the segments that showed hyperenhancement of >50% of tissue on late-enhanced MRI. In these segments, preserved SWT was observed in 15 of 33 segments (45%) with first-pass hypoenhancement of < or =50% of tissue, but in only 2 of 22 segments (9%) with first-pass hypoenhancement of >50% of tissue. CONCLUSION: Whereas the diagnostic capability of first-pass MRI alone is limited, complementary use of first-pass MRI can enhance the diagnostic performance of late-enhanced MRI because hypoenhancement during first-pass imaging is more specific to nonviable myocardium.
PURPOSE: The aim of this study was to determine the comparative diagnostic values of late gadolinium-enhanced magnetic resonance imaging (MRI) and first-pass dynamic MRI for predicting functional recovery of regional myocardial contraction in patients early after acute myocardial infarction. MATERIALS AND METHODS: First-pass and late-enhanced MRI were performed in 18 patients 5.5 +/- 2.5 days after the onset of myocardial infarction. Images analysis was performed using a 12-segment model. Regional systolic wall thickening (SWT) was measured on cine-MRI obtained 273 +/- 130 days later. RESULTS: Late-enhanced MRI revealed hyperenhancement in all patients, whereas hypoenhancement on first-pass MRI was observed in 67% (12/18) of the patients. The area under the receiver operating characteristics curve was 0.86 for late-enhanced MRI and 0.74 for first-pass MRI (P = 0.27). First-pass MRI was useful for predicting functional recovery of the segments that showed hyperenhancement of >50% of tissue on late-enhanced MRI. In these segments, preserved SWT was observed in 15 of 33 segments (45%) with first-pass hypoenhancement of < or =50% of tissue, but in only 2 of 22 segments (9%) with first-pass hypoenhancement of >50% of tissue. CONCLUSION: Whereas the diagnostic capability of first-pass MRI alone is limited, complementary use of first-pass MRI can enhance the diagnostic performance of late-enhanced MRI because hypoenhancement during first-pass imaging is more specific to nonviable myocardium.
Authors: Andrew T Yan; Adolphe J Shayne; Kenneth A Brown; Sandeep N Gupta; Carmen W Chan; Tuan M Luu; Marcelo F Di Carli; H Glenn Reynolds; William G Stevenson; Raymond Y Kwong Journal: Circulation Date: 2006-06-26 Impact factor: 29.690
Authors: K C Wu; E A Zerhouni; R M Judd; C H Lugo-Olivieri; L A Barouch; S P Schulman; R S Blumenthal; J A Lima Journal: Circulation Date: 1998-03-03 Impact factor: 29.690
Authors: Manesh R Patel; Timothy S E Albert; David E Kandzari; Emily F Honeycutt; Linda K Shaw; Michael H Sketch; Michael D Elliott; Robert M Judd; Raymond J Kim Journal: Radiology Date: 2006-09 Impact factor: 11.105
Authors: L Natale; C Napolitano; A Bernardini; A Meduri; R Marano; A Lombardo; F Crea; L Bonomo Journal: Radiol Med Date: 2012-03-19 Impact factor: 3.469