PURPOSE: To compare contrast material-enhanced magnetic resonance (MR) imaging with resting thallium 201 ((201)Tl) single photon emission computed tomography (SPECT) for predicting myocardial viability in patients early after acute myocardial infarction. MATERIALS AND METHODS: Inversion-recovery contrast-enhanced MR images and resting (201)Tl SPECT images were obtained in 22 patients after acute myocardial infarction. The (201)Tl SPECT images were obtained 4.3 days +/- 0.2 (standard error) after the onset of myocardial infarction. Contrast-enhanced MR imaging was performed 7.9 days +/- 1.6 after (201)Tl SPECT. Transmural extent of hyperenhancement on contrast-enhanced MR images and regional (201)Tl activity were quantitatively analyzed with a 12-segment model. Regional wall thickening on follow-up cine MR images obtained 67 days +/- 17 after contrast-enhanced MR imaging was used as an index for myocardial viability. Statistical analyses were performed with the chi(2) and two-tailed Student t tests. RESULTS: Both contrast-enhanced MR and resting (201)Tl SPECT images showed significant correlations with regional wall thickening on follow-up cine MR images. The sensitivity, specificity, and accuracy of contrast-enhanced MR imaging in the prediction of viable myocardium were significantly higher than those of resting (201)Tl SPECT (98.0% vs 90.3%, P <.01; 75.0% vs 54.4%, P <.05; and 92.0% vs 81.1%, P <.001, respectively). CONCLUSION: Delayed contrast-enhanced MR imaging can help predict myocardial viability as seen on follow-up cine MR images after acute myocardial infarction, with significantly improved sensitivity, specificity, and accuracy in comparison with those of resting (201)Tl SPECT. Copyright RSNA, 2002
PURPOSE: To compare contrast material-enhanced magnetic resonance (MR) imaging with resting thallium 201 ((201)Tl) single photon emission computed tomography (SPECT) for predicting myocardial viability in patients early after acute myocardial infarction. MATERIALS AND METHODS: Inversion-recovery contrast-enhanced MR images and resting (201)Tl SPECT images were obtained in 22 patients after acute myocardial infarction. The (201)Tl SPECT images were obtained 4.3 days +/- 0.2 (standard error) after the onset of myocardial infarction. Contrast-enhanced MR imaging was performed 7.9 days +/- 1.6 after (201)Tl SPECT. Transmural extent of hyperenhancement on contrast-enhanced MR images and regional (201)Tl activity were quantitatively analyzed with a 12-segment model. Regional wall thickening on follow-up cine MR images obtained 67 days +/- 17 after contrast-enhanced MR imaging was used as an index for myocardial viability. Statistical analyses were performed with the chi(2) and two-tailed Student t tests. RESULTS: Both contrast-enhanced MR and resting (201)Tl SPECT images showed significant correlations with regional wall thickening on follow-up cine MR images. The sensitivity, specificity, and accuracy of contrast-enhanced MR imaging in the prediction of viable myocardium were significantly higher than those of resting (201)Tl SPECT (98.0% vs 90.3%, P <.01; 75.0% vs 54.4%, P <.05; and 92.0% vs 81.1%, P <.001, respectively). CONCLUSION: Delayed contrast-enhanced MR imaging can help predict myocardial viability as seen on follow-up cine MR images after acute myocardial infarction, with significantly improved sensitivity, specificity, and accuracy in comparison with those of resting (201)Tl SPECT. Copyright RSNA, 2002
Authors: Tomas Skala; Martin Hutyra; Jan Vaclavik; Milan Kaminek; David Horak; Josef Novotny; Jana Zapletalova; Jan Lukl; Dan Marek; Milos Taborsky Journal: Int J Cardiovasc Imaging Date: 2010-08-20 Impact factor: 2.357
Authors: David S Fieno; Louise E J Thomson; Piotr Slomka; Aiden Abidov; John D Friedman; Guido Germano; Daniel S Berman Journal: J Nucl Cardiol Date: 2007-01 Impact factor: 5.952
Authors: Guenter Pilz; Peter Bernhardt; Markus Klos; Eman Ali; Michael Wild; Berthold Höfling Journal: Clin Res Cardiol Date: 2006-08-16 Impact factor: 5.460
Authors: Mohammad Haris; Anup Singh; Kejia Cai; Feliks Kogan; Jeremy McGarvey; Catherine Debrosse; Gerald A Zsido; Walter R T Witschey; Kevin Koomalsingh; James J Pilla; Julio A Chirinos; Victor A Ferrari; Joseph H Gorman; Hari Hariharan; Robert C Gorman; Ravinder Reddy Journal: Nat Med Date: 2014-01-12 Impact factor: 53.440
Authors: Michael Salerno; Laine Elliot; Linda K Shaw; Jonathan P Piccini; Robert Pagnanelli; Salvador Borges-Neto Journal: J Nucl Cardiol Date: 2009-06-03 Impact factor: 5.952
Authors: Lene Rosendahl; Peter Blomstrand; Jan L Ohlsson; Per-Gunnar Björklund; Britt-Marie Ahlander; Sven-Ake Starck; Jan E Engvall Journal: BMC Med Imaging Date: 2008-12-12 Impact factor: 1.930