Literature DB >> 17629283

Properties of astaxanthin/Ca2+ complex formation in the deceleration of cis/trans isomerization.

Chien-Sheng Chen1, Shih-Hsiung Wu, Ying-Ying Wu, Jim-Min Fang, Tzu-Hua Wu.   

Abstract

Deceleration of the regioselective cis/trans isomerization of all-trans-astaxanthin (ASTX) in the presence of Ca2+ was shown by HPLC analysis. The NMR and ITC analyses provided evidence for complexation of ASTX with Ca2+ in 1:2 stoichiometry via chelation at both carbonyl and hydroxyl groups. The rotation across torsion omega6 (C5-C6-C7-C8) upon complexation is consistent with the NOE between 7-H and 5-CH3. This study supports the inhibitory effect of ASTX on calcium-induced turbidity of lens crystallins.

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Year:  2007        PMID： 17629283     DOI： 10.1021/ol0709533

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  Assignment of absolute configuration to SCH 351448 via total synthesis.

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Journal:  Org Lett       Date:  2008-06-11       Impact factor: 6.005

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Journal:  J Neural Transm (Vienna)       Date:  2016-09-17       Impact factor: 3.575

3.  Free radical formation in novel carotenoid metal ion complexes of astaxanthin.

Authors:  Nikolay E Polyakov; A Ligia Focsan; Michael K Bowman; Lowell D Kispert
Journal:  J Phys Chem B       Date:  2010-11-29       Impact factor: 2.991

4.  Role of pirenoxine in the effects of catalin on in vitro ultraviolet-induced lens protein turbidity and selenite-induced cataractogenesis in vivo.

Authors:  Chao-Chien Hu; Jiahn-Haur Liao; Kuang-Yang Hsu; I-Lin Lin; Ming-Hsuan Tsai; Wen-Hsin Wu; Tzu-Tang Wei; Yi-Shiang Huang; Shih-Jiuan Chiu; Hsiang-Yin Chen; Shih-Hsiung Wu; Tzu-Hua Wu
Journal:  Mol Vis       Date:  2011-07-12       Impact factor: 2.367

Review 5.  Heat Shock Proteins and Autophagy Pathways in Neuroprotection: from Molecular Bases to Pharmacological Interventions.

Authors:  Botond Penke; Ferenc Bogár; Tim Crul; Miklós Sántha; Melinda E Tóth; László Vígh
Journal:  Int J Mol Sci       Date:  2018-01-22       Impact factor: 5.923

6.  The metal cation chelating capacity of astaxanthin. Does this have any influence on antiradical activity?

Authors:  Elizabeth Hernández-Marin; Andrés Barbosa; Ana Martínez
Journal:  Molecules       Date:  2012-01-20       Impact factor: 4.411
  6 in total

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