| Literature DB >> 17625259 |
Christian Nern1, Stefan Momma.
Abstract
This review gives an overview of current issues concerning the application of the concept of the stem cell niche to the adult mammalian brain. It describes how the niche manifests itself at different structural levels as well as the main applications that are influenced by this concept. Finally, special regard is given to what is known for the adult human brain and how far the findings from lower animals can be applied in harnessing the regenerative potential of stem cells for therapy.Entities:
Mesh:
Year: 2006 PMID: 17625259 DOI: 10.1007/s12015-006-0051-6
Source DB: PubMed Journal: Stem Cell Rev ISSN: 1550-8943 Impact factor: 5.739