Literature DB >> 17624792

Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.

D L A Rakotondramanana1, Mélanie Delomenède, Michel Baltas, Hubert Duran, Florence Bedos-Belval, Philippe Rasoanaivo, Anne Negre-Salvayre, Heinz Gornitzka.   

Abstract

Oxidative dimerization of ferulic acid methyl ester afforded dihydrobenzofuran derivative and new linear compound identified by X-ray crystallography. The gallate derivatized dihydrobenzofuran analogue was obtained and all compounds were evaluated for potential antiatherogenic, antiplasmodial (best IC(50)=0.8 microM) and cytotoxic activities.

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Year:  2007        PMID: 17624792     DOI: 10.1016/j.bmc.2007.06.047

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  Identification of (-)(E)-N-[2(S)-Hydroxy-2-(4-hydroxyphenyl) ethyl]ferulamide, a natural product isolated from Croton pullei: theoretical and experimental analysis.

Authors:  Silvana de O Silva; Rosana N S Peixoto; José Rogério A Silva; Cláudio N Alves; Giselle M S P Guilhon; Lourivaldo S Santos; Davi do S B Brasil
Journal:  Int J Mol Sci       Date:  2011-12-15       Impact factor: 5.923

Review 2.  Bioinspired syntheses of dimeric hydroxycinnamic acids (lignans) and hybrids, using phenol oxidative coupling as key reaction, and medicinal significance thereof.

Authors:  George E Magoulas; Dionissios Papaioannou
Journal:  Molecules       Date:  2014-11-28       Impact factor: 4.411

  2 in total

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