OBJECTIVE: To evaluate whether some cancers, other conditions, and pregnancy outcomes were related to occupational perfluorooctane sulfonate (PFOS) exposure. METHODS: We surveyed current and former employees of a perfluorooctanesulfonyl fluoride production facility, using a self-administered questionnaire to ascertain several cancers and health conditions. Female cohort members also completed a brief pregnancy history. We requested medical records to validate reported melanoma, breast, prostate, and colon cancers. PFOS exposure was estimated based on a job exposure matrix up to the year of the diagnosis of the condition. RESULTS: Of the 1,895 eligible participants, 1,400 questionnaires were returned. No association was observed between working in a PFOS-exposed job and the risk of any of the surveyed conditions. CONCLUSION: We observed no association between working in a PFOS-exposed job and several cancers, common health conditions, and birth weight.
OBJECTIVE: To evaluate whether some cancers, other conditions, and pregnancy outcomes were related to occupational perfluorooctane sulfonate (PFOS) exposure. METHODS: We surveyed current and former employees of a perfluorooctanesulfonyl fluoride production facility, using a self-administered questionnaire to ascertain several cancers and health conditions. Female cohort members also completed a brief pregnancy history. We requested medical records to validate reported melanoma, breast, prostate, and colon cancers. PFOS exposure was estimated based on a job exposure matrix up to the year of the diagnosis of the condition. RESULTS: Of the 1,895 eligible participants, 1,400 questionnaires were returned. No association was observed between working in a PFOS-exposed job and the risk of any of the surveyed conditions. CONCLUSION: We observed no association between working in a PFOS-exposed job and several cancers, common health conditions, and birth weight.
Authors: Kristina W Whitworth; Line S Haug; Donna D Baird; Georg Becher; Jane A Hoppin; Rolv Skjaerven; Cathrine Thomsen; Merete Eggesbo; Gregory Travlos; Ralph Wilson; Lea A Cupul-Uicab; Anne Lise Brantsaeter; Matthew P Longnecker Journal: Am J Epidemiol Date: 2012-04-19 Impact factor: 4.897
Authors: Benjamin J Apelberg; Frank R Witter; Julie B Herbstman; Antonia M Calafat; Rolf U Halden; Larry L Needham; Lynn R Goldman Journal: Environ Health Perspect Date: 2007-11 Impact factor: 9.031