Literature DB >> 17620386

Histatin-derived monomeric and dimeric synthetic peptides show strong bactericidal activity towards multidrug-resistant Staphylococcus aureus in vivo.

Mick M Welling1, Carlo P J M Brouwer, Wim van 't Hof, Enno C I Veerman, Arie V Nieuw Amerongen.   

Abstract

Homodimerization of histatin-derived peptides generally led to improved bactericidal activity against Staphylococcus aureus in vitro. In vivo, monomers and dimers were equally active in killing bacteria in mice with a soft tissue infection. Altogether, these peptides are promising compounds for the development of novel therapeutics against infections with drug-resistant bacteria.

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Year:  2007        PMID： 17620386      PMCID： PMC2043174          DOI： 10.1128/AAC.00196-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

Review 1.  Antimicrobial peptides: properties and applicability.

Authors:  W van 't Hof; E C Veerman; E J Helmerhorst; A V Amerongen
Journal:  Biol Chem       Date:  2001-04       Impact factor: 3.915

2.  Epitope mapping of the Dermatophagoides pteronyssinus house dust mite major allergen Der p II using overlapping synthetic peptides.

Authors:  W van 't Hof; P C Driedijk; M van den Berg; A G Beck-Sickinger; G Jung; R C Aalberse
Journal:  Mol Immunol       Date:  1991-11       Impact factor: 4.407

3.  Synthetic peptides derived from human antimicrobial peptide ubiquicidin accumulate at sites of infections and eradicate (multi-drug resistant) Staphylococcus aureus in mice.

Authors:  Carlo P J M Brouwer; Sylvia J P Bogaards; Marty Wulferink; Markwin P Velders; Mick M Welling
Journal:  Peptides       Date:  2006-07-11       Impact factor: 3.750

4.  Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations.

Authors:  M M Welling; A Paulusma-Annema; H S Balter; E K Pauwels; P H Nibbering
Journal:  Eur J Nucl Med       Date:  2000-03

5.  Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

Authors:  J P Tam
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

6.  Effects of histatin 5 and derived peptides on Candida albicans.

Authors:  A L Ruissen; J Groenink; E J Helmerhorst; E Walgreen-Weterings; W Van't Hof; E C Veerman; A V Nieuw Amerongen
Journal:  Biochem J       Date:  2001-06-01       Impact factor: 3.857

7.  Radiochemical and biological characteristics of 99mTc-UBI 29-41 for imaging of bacterial infections.

Authors:  Mick M Welling; Sandra Mongera; Antonella Lupetti; Henia S Balter; Valeria Bonetto; Ulderico Mazzi; Ernest K J Pauwels; Peter H Nibbering
Journal:  Nucl Med Biol       Date:  2002-05       Impact factor: 2.408

8.  Degradation of antimicrobial histatin-variant peptides in Staphylococcus aureus and Streptococcus mutans.

Authors:  J Groenink; A L A Ruissen; D Lowies; W van 't Hof; E C I Veerman; A V Nieuw Amerongen
Journal:  J Dent Res       Date:  2003-09       Impact factor: 6.116

9.  Structural relationship between human salivary histatins.

Authors:  R F Troxler; G D Offner; T Xu; J C Vanderspek; F G Oppenheim
Journal:  J Dent Res       Date:  1990-01       Impact factor: 6.116

10.  Potential therapeutic role of histatin derivative P-113d in experimental rat models of Pseudomonas aeruginosa sepsis.

Authors:  Oscar Cirioni; Andrea Giacometti; Roberto Ghiselli; Fiorenza Orlando; Wojciech Kamysz; Giuseppina D'Amato; Federico Mocchegiani; Jerzy Lukasiak; Carmela Silvestri; Vittorio Saba; Giorgio Scalise
Journal:  J Infect Dis       Date:  2004-06-21       Impact factor: 5.226
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  8 in total

1.  Effects of dimerization on the structure and biological activity of antimicrobial peptide Ctx-Ha.

Authors:  E N Lorenzón; G F Cespedes; E F Vicente; L G Nogueira; T M Bauab; M S Castro; E M Cilli
Journal:  Antimicrob Agents Chemother       Date:  2012-03-05       Impact factor: 5.191

2.  Antibacterial Peptides: Opportunities for the Prevention and Treatment of Dental Caries.

Authors:  Adam Pepperney; Michael L Chikindas
Journal:  Probiotics Antimicrob Proteins       Date:  2011-06       Impact factor: 4.609

Review 3.  Efficiency of Antimicrobial Peptides Against Multidrug-Resistant Staphylococcal Pathogens.

Authors:  Mi Nguyen-Tra Le; Miki Kawada-Matsuo; Hitoshi Komatsuzawa
Journal:  Front Microbiol       Date:  2022-06-09       Impact factor: 6.064

4.  The Antimicrobial Peptides P-113Du and P-113Tri Function against Candida albicans.

Authors:  Guan-Yu Lin; Hsueh-Fen Chen; Yao-Peng Xue; Ying-Chieh Yeh; Chia-Lu Chen; Ming-Sun Liu; Wen-Chi Cheng; Chung-Yu Lan
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

5.  Histatin 5-spermidine conjugates have enhanced fungicidal activity and efficacy as a topical therapeutic for oral candidiasis.

Authors:  Swetha Tati; Rui Li; Sumant Puri; Rohitashw Kumar; Peter Davidow; Mira Edgerton
Journal:  Antimicrob Agents Chemother       Date:  2013-11-18       Impact factor: 5.191

Review 6.  Endogenous antimicrobial factors in the treatment of infectious diseases.

Authors:  Paulina Żelechowska; Justyna Agier; Ewa Brzezińska-Błaszczyk
Journal:  Cent Eur J Immunol       Date:  2017-01-24       Impact factor: 2.085

Review 7.  Innate Inspiration: Antifungal Peptides and Other Immunotherapeutics From the Host Immune Response.

Authors:  Derry K Mercer; Deborah A O'Neil
Journal:  Front Immunol       Date:  2020-09-17       Impact factor: 7.561

8.  Specific metallo-protein interactions and antimicrobial activity in Histatin-5, an intrinsically disordered salivary peptide.

Authors:  Tyler G McCaslin; Cynthia V Pagba; Jiby Yohannan; Bridgette A Barry
Journal:  Sci Rep       Date:  2019-11-21       Impact factor: 4.379
  8 in total

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