Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The Antimicrobial Peptides P-113Du and P-113Tri Function against Candida albicans.

Literature DB >> 27458227

The Antimicrobial Peptides P-113Du and P-113Tri Function against Candida albicans.

Guan-Yu Lin¹, Hsueh-Fen Chen¹, Yao-Peng Xue², Ying-Chieh Yeh¹, Chia-Lu Chen¹, Ming-Sun Liu³, Wen-Chi Cheng⁴, Chung-Yu Lan⁵.

Abstract

Two antimicrobial P-113 peptide derivatives, P-113Du and P-113Tri, were investigated in this study. Notably, P-113Du and P-113Tri contained significant fractions of α-helix conformation and were less sensitive to high salt and low pH than P-113. Moreover, compared to P-113, these peptides exhibited increased antifungal activity against planktonic cells, biofilm cells, and clinical isolates of Candida albicans and non-albicans Candida spp. These results suggest that P-113Du and P-113Tri are promising candidates for development as novel antifungal agents.

Entities: Chemical Species

Mesh：

Substances：

Year: 2016 PMID： 27458227 PMCID： PMC5038333 DOI： 10.1128/AAC.00699-16

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

31 in total

1. Scanning electron microscopy of Candida albicans after in vitro treatment with miconazole.

Authors: S De Nollin; M Borgers
Journal: Antimicrob Agents Chemother Date: 1975-05 Impact factor: 5.191

2. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides.

Authors: Margaret A Schmitt; Bernard Weisblum; Samuel H Gellman
Journal: J Am Chem Soc Date: 2007-01-17 Impact factor: 15.419

4. The interaction Between Carbohydrates and the Antimicrobial Peptide P-113Tri is Involved in the Killing of Candida albicans.

Authors: Guan-Yu Lin; Chuan-Fa Chang; Chung-Yu Lan
Journal: Microorganisms Date: 2020-02-21

5. Antimicrobial Activity of the Peptide LfcinB15 against Candida albicans.

Authors: Che-Kang Chang; Mou-Chieh Kao; Chung-Yu Lan
Journal: J Fungi (Basel) Date: 2021-06-29

5 in total

The Antimicrobial Peptides P-113Du and P-113Tri Function against Candida albicans.

1. Scanning electron microscopy of Candida albicans after in vitro treatment with miconazole.

2. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides.

3. Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans.

4. Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy.

5. Susceptibility of Candida biofilms to histatin 5 and fluconazole.

6. Synthetic histatin analogues with broad-spectrum antimicrobial activity.

7. Candidacidal activity of recombinant human salivary histatin-5 and variants.

8. Effect of marine polyunsaturated fatty acids on biofilm formation of Candida albicans and Candida dubliniensis.

9. Role of SFP1 in the Regulation of Candida albicans Biofilm Formation.

10. Characterization of Antimicrobial Peptides toward the Development of Novel Antibiotics.

1. Effect of Dermaseptin S4 on C. albicans Growth and EAP1 and HWP1 Gene Expression.

Review 2. Innate Inspiration: Antifungal Peptides and Other Immunotherapeutics From the Host Immune Response.

3. Novel mitochondrial complex I-inhibiting peptides restrain NADH dehydrogenase activity.

4. The interaction Between Carbohydrates and the Antimicrobial Peptide P-113Tri is Involved in the Killing of Candida albicans.

5. Antimicrobial Activity of the Peptide LfcinB15 against Candida albicans.