Literature DB >> 1761083

Effects of parenteral diclofenac sodium on upper gastrointestinal motility after food in man.

G Bassotti1, G Bucaneve, C Betti, L Patoia, E Baratta, V Maresca, M A Pelli, A Morelli, A Del Favero.   

Abstract

In experimental animal models nonsteroidal anti-inflammatory drugs may influence gastrointestinal motility, but as evidence is lacking in man. The effect of diclofenac sodium 75 mg i.m. on the motor response of the upper gastrointestinal tract to food has been studied by manometry in 9 healthy volunteers. Diclofenac had no effect on the motor activity of the stomach, duodenum, or jejunum after a 605 kcal meal.

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Year:  1991        PMID： 1761083     DOI： 10.1007/BF00626379

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  23 in total

1.  Gastric motility is an important factor in the pathogenesis of indomethacin-induced gastric mucosal lesions in rats.

Authors:  S Ueki; K Takeuchi; S Okabe
Journal:  Dig Dis Sci       Date:  1988-02       Impact factor: 3.199

2.  Does endogenous prostaglandin affect gastric antral motility?

Authors:  K M Sanders; J H Szurszewski
Journal:  Am J Physiol       Date:  1981-08

3.  Normal patterns of human upper small bowel motor activity recorded by prolonged radiotelemetry.

Authors:  D G Thompson; D L Wingate; L Archer; M J Benson; W J Green; R J Hardy
Journal:  Gut       Date:  1980-06       Impact factor: 23.059

4.  Role of prostaglandins in tone and effector reactivity of the isolated rat stomach preparation.

Authors:  A L Frankhuijzen; I L Bonta
Journal:  Eur J Pharmacol       Date:  1975-03       Impact factor: 4.432

5.  Nonsteroidal antiinflammatory drugs: effect on pyloric sphincter and duodenogastric reflux.

Authors:  J L Pantoja; C Defilippi; J E Valenzuela; A Csendes
Journal:  Dig Dis Sci       Date:  1979-03       Impact factor: 3.199

6.  Manometric evaluation of functional upper gut symptoms.

Authors:  J R Malagelada; V Stanghellini
Journal:  Gastroenterology       Date:  1985-05       Impact factor: 22.682

7.  Variability of motility of the ileum and jejunum in healthy humans.

Authors:  P Kerlin; S Phillips
Journal:  Gastroenterology       Date:  1982-04       Impact factor: 22.682

8.  Gastrointestinal myoelectric activity disturbances in gastric ulcer disease in rats and dogs.

Authors:  J Fioramonti; L Bueno
Journal:  Dig Dis Sci       Date:  1980-08       Impact factor: 3.199

9.  Stress-induced gastroduodenal motor disturbances in humans: possible humoral mechanisms.

Authors:  V Stanghellini; J R Malagelada; A R Zinsmeister; V L Go; P C Kao
Journal:  Gastroenterology       Date:  1983-07       Impact factor: 22.682

10.  Functional dyspepsia and chronic idiopathic gastric stasis. Role of endogenous opiates.

Authors:  F Narducci; G Bassotti; M T Granata; M Gaburri; F Farroni; R Palumbo; A Morelli
Journal:  Arch Intern Med       Date:  1986-04
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  4 in total

1.  Effects of octreotide on manometric variables in patients with neuropathic abnormalities of the small bowel.

Authors:  G Bassotti; U Germani; C Calcara; F Spinozzi; P Roselli; A Morelli
Journal:  Dig Dis Sci       Date:  1997-08       Impact factor: 3.199

2.  Abnormal gastrointestinal motility in patients with celiac sprue.

Authors:  G Bassotti; G Castellucci; C Betti; C Fusaro; M L Cavalletti; A Bertotto; F Spinozzi; A Morelli; M A Pelli
Journal:  Dig Dis Sci       Date:  1994-09       Impact factor: 3.199

Review 3.  Pharmacokinetic considerations in gastrointestinal motor disorders.

Authors:  G S Hebbard; W M Sun; F Bochner; M Horowitz
Journal:  Clin Pharmacokinet       Date:  1995-01       Impact factor: 6.447

4.  Double-blind, placebo-controlled study on effects of diclofenac sodium and indomethacin on postprandial gastric motility in man.

Authors:  G Bassotti; G Bucaneve; P Furno; A Morelli; A Del Favero
Journal:  Dig Dis Sci       Date:  1998-06       Impact factor: 3.199
  4 in total

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