Literature DB >> 17608753

Evaluation of the use of PTQ implants for the treatment of incontinent patients due to internal anal sphincter dysfunction.

F de la Portilla1, A Fernández, E León, R Rada, N Cisneros, V H Maldonado, J Vega, E Espinosa.   

Abstract

OBJECTIVE: This study reports the results of injectable silicone PTQ implants for faecal incontinence due to internal anal sphincter (IAS) dysfunction.
METHOD: Twenty patients (12 women) with partial faecal incontinence aged from 55 to 65 years were treated by a PTQ implant. All patients completed the Cleveland Clinic Continence and Quality of Life questionnaire. Endoluminal ultrasound and anorectal physiological testing were performed in each patient. All implants were inserted into the submucosal plane without ultrasound guidance.
RESULTS: Faecal continence was significantly improved up to 1 year. The Wexner continence score fell from a median of 13.05 (range, 5-20) before treatment to 4.5 (range 2-7.7) at 1 month after (P < 0.005). This rose gradually to 6.2 (range, 0-16) at one year (P = 0.02) and 9.4 (range, 1-20) at 2 years (P = 0.127). There were no differences in resting or squeeze pressure before and at 3 months after treatment (P = 0.86 and P = 0.93). Fourteen (70%) patients experienced pruritus ani during the first few weeks after the procedure and one developed infection at the implant site.
CONCLUSION: Silicone implantation is minimally invasive and technically simple. It is effective over 1 year in the treatment of faecal incontinence due to IAS dysfunction.

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Year:  2007        PMID: 17608753     DOI: 10.1111/j.1463-1318.2007.01276.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  12 in total

1.  Evaluation by three-dimensional anal endosonography of injectable silicone biomaterial (PTQ) implants to treat fecal incontinence: long-term localization and relation with the deterioration of the continence.

Authors:  F de la Portilla; J Vega; R Rada; M M Segovia-Gonzáles; N Cisneros; V H Maldonado; E Espinosa
Journal:  Tech Coloproctol       Date:  2009-07-15       Impact factor: 3.781

Review 2.  Current status: new technologies for the treatment of patients with fecal incontinence.

Authors:  Andreas M Kaiser; Guy R Orangio; Massarat Zutshi; Suraj Alva; Tracy L Hull; Peter W Marcello; David A Margolin; Janice F Rafferty; W Donald Buie; Steven D Wexner
Journal:  Surg Endosc       Date:  2014-03-08       Impact factor: 4.584

Review 3.  Posterior tibial nerve stimulation and faecal incontinence: a review.

Authors:  John M Findlay; Charles Maxwell-Armstrong
Journal:  Int J Colorectal Dis       Date:  2010-11-11       Impact factor: 2.571

4.  Short-term outcome of percutaneous posterior tibial nerve stimulation (PTNS) for the treatment of faecal incontinence.

Authors:  E Peña Ros; P A Parra Baños; J A Benavides Buleje; J M Muñoz Camarena; C Escamilla Segade; M F Candel Arenas; F M Gonzalez Valverde; A Albarracín Marín-Blázquez
Journal:  Tech Coloproctol       Date:  2016-01       Impact factor: 3.781

5.  Comparison of bulking agents in the treatment of fecal incontinence: a prospective randomized clinical trial.

Authors:  O J Morris; S Smith; B Draganic
Journal:  Tech Coloproctol       Date:  2013-03-23       Impact factor: 3.781

6.  Reinterventions after complicated or failed STARR procedure.

Authors:  Mario Pescatori; Andrew P Zbar
Journal:  Int J Colorectal Dis       Date:  2008-08-12       Impact factor: 2.571

7.  The use of Permacol® injections for the treatment of faecal incontinence.

Authors:  Zeiad I Hussain; Michael Lim; Haider Mussa; Kazim Abbas; Stevan Stojkovic
Journal:  Updates Surg       Date:  2012-09-05

8.  Treatment of fecal incontinence - review of observational studies (OS) and randomized controlled trials (RCT) related to injection of bulking agent into peri-anal tissue.

Authors:  Felix W Leung
Journal:  J Interv Gastroenterol       Date:  2011-10-01

9.  An Open-Label, Noncomparative, Multicenter Study to Evaluate Efficacy and Safety of NASHA/Dx Gel as a Bulking Agent for the Treatment of Fecal Incontinence.

Authors:  Giuseppe Dodi; Johannes Jongen; Fernando de la Portilla; Manoj Raval; Donato F Altomare; Paul-Antoine Lehur
Journal:  Gastroenterol Res Pract       Date:  2010-12-27       Impact factor: 2.260

10.  A prospective non-randomized two-centre study of patients with passive faecal incontinence after birth trauma and patients with soiling after anal surgery, treated by elastomer implants versus rectal irrigation.

Authors:  S J van der Hagen; W van der Meer; P B Soeters; C G Baeten; W G van Gemert
Journal:  Int J Colorectal Dis       Date:  2012-05-11       Impact factor: 2.571

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