Literature DB >> 17602597

Three-component combinatorial synthesis of a substituted 6H-pyrido[2',1':2,3]imidazo- [4,5-c]isoquinolin-5(6H)-one library with cytotoxic activity.

Tao Meng1, Zhixiang Zhang, Dingyu Hu, Liping Lin, Jian Ding, Xin Wang, Jingkang Shen.   

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Year:  2007        PMID： 17602597     DOI： 10.1021/cc0700593

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


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  3 in total

Review 1.  Groebke-Blackburn-Bienaymé multicomponent reaction: emerging chemistry for drug discovery.

Authors:  Saad Shaaban; Bakr F Abdel-Wahab
Journal:  Mol Divers       Date:  2015-05-28       Impact factor: 2.943

2.  6-Benzyl-3,4-dimeth-oxy-10-methyl-pyrido[2',1':2,3]imidazo[4,5-c]isoquinolin-5(6H)-one.

Authors:  Kathrin Meindl; Daniel Stern; Fadime Mert-Balci; Uwe Beifuss
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-09-12

3.  MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.

Authors:  Zhixiang Zhang; Tao Meng; Jingxue He; Ming Li; Lin-Jiang Tong; Bing Xiong; Liping Lin; Jingkang Shen; Ze-Hong Miao; Jian Ding
Journal:  Invest New Drugs       Date:  2009-08-25       Impact factor: 3.850
  3 in total

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