Literature DB >> 17595099

A general and practical method of alkynyl indole and benzofuran synthesis via tandem Cu- and Pd-catalyzed cross-couplings.

Masatoshi Nagamochi1, Yuan-Qing Fang, Mark Lautens.   

Abstract

A new tandem coupling approach to synthesize 2-alkynyl indoles and benzofurans is described. This reaction utilizes easily accessible gem-dibromovinyl substrates and terminal alkynes and proceeds via Pd/C- and CuI-catalyzed tandem Ullman/Sonogashira couplings.

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Year:  2007        PMID： 17595099     DOI： 10.1021/ol071370w

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  A sequential metal-catalyzed C-N bond formation in the synthesis of 2-amido-indoles.

Authors:  Pei-Yuan Yao; Yu Zhang; Richard P Hsung; Kang Zhao
Journal:  Org Lett       Date:  2008-08-28       Impact factor: 6.005

2.  Nickel Catalyzed Vinylidene Insertions into O-H Bonds.

Authors:  Houng Kang; Christopher Uyeda
Journal:  ACS Catal       Date:  2020-12-15       Impact factor: 13.084

Review 3.  Recent advances in the synthesis of N-containing heteroaromatics via heterogeneously transition metal catalysed cross-coupling reactions.

Authors:  Laurent Djakovitch; Nelly Batail; Marie Genelot
Journal:  Molecules       Date:  2011-06-23       Impact factor: 4.411

4.  Palladium-catalyzed cross-coupling reaction of alkenyl aluminums with 2-bromobenzo[b]furans.

Authors:  Chang Wen; Xin Jiang; Kun Wu; Ruiqiang Luo; Qinghan Li
Journal:  RSC Adv       Date:  2020-05-22       Impact factor: 4.036

5.  Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles.

Authors:  Rajesh K Arigela; Sudhir K Sharma; Brijesh Kumar; Bijoy Kundu
Journal:  Beilstein J Org Chem       Date:  2013-02-19       Impact factor: 2.883
  5 in total

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