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Literature DB >> 17594030

Reversible folding-unfolding, aggregation protection, and multi-year stabilization, in high concentration protein solutions, using ionic liquids.

Nolene Byrne¹, Li-Min Wang, Jean-Philippe Belieres, C Austen Angell.

Abstract

We report the reversible thermal unfolding/refolding, and long period stabilization against aggregation and hydrolysis, of >200 mg ml(-1) solutions of lysozyme in ionic liquid-rich, ice-avoiding, solvents.

Entities: Gene

Mesh：

Substances：
Ions
Proteins
Solutions

Year: 2007 PMID： 17594030 DOI： 10.1039/b618943a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

15 in total

Review 1. Room-temperature ionic liquids meet bio-membranes: the state-of-the-art.

Authors: Antonio Benedetto
Journal: Biophys Rev Date: 2017-08-04

2. Comparison of three ionic liquid-tolerant cellulases by molecular dynamics.

Authors: Vance Jaeger; Patrick Burney; Jim Pfaendtner
Journal: Biophys J Date: 2015-02-17 Impact factor: 4.033

3. In vitro assessment of choline dihydrogen phosphate (CDHP) as a vehicle for recombinant human interleukin-2 (rhIL-2).

Authors: David M Foureau; Regina M Vrikkis; Chase P Jones; Katherine D Weaver; Douglas R Macfarlane; Jonathan C Salo; Iain H McKillop; Gloria D Elliott
Journal: Cell Mol Bioeng Date: 2012-12-01 Impact factor: 2.321

4. Effects of protein and phosphate buffer concentrations on thermal denaturation of lysozyme analyzed by isoconversional method.

Authors: X M Cao; Y Tian; Z Y Wang; Y W Liu; C X Wang
Journal: Bioengineered Date: 2016-07-03 Impact factor: 3.269

Reversible folding-unfolding, aggregation protection, and multi-year stabilization, in high concentration protein solutions, using ionic liquids.

Review 1. Room-temperature ionic liquids meet bio-membranes: the state-of-the-art.

2. Comparison of three ionic liquid-tolerant cellulases by molecular dynamics.

3. In vitro assessment of choline dihydrogen phosphate (CDHP) as a vehicle for recombinant human interleukin-2 (rhIL-2).

4. Effects of protein and phosphate buffer concentrations on thermal denaturation of lysozyme analyzed by isoconversional method.

Review 5. Effect of water and ionic liquids on biomolecules.

6. Ionic liquids in protein amyloidogenesis: a brief screenshot of the state-of-the-art.

7. Sulfadiazine binds and unfolds bovine serum albumin: an in vitro study.

8. Fluorescence and circular dichroism spectroscopy of cytochrome c in alkylammonium formate ionic liquids.

9. Choline dihydrogen phosphate.

10. Efficient Sustainable Tool for Monitoring Chemical Reactions and Structure Determination in Ionic Liquids by ESI-MS.