Literature DB >> 17586674

Newly discovered penicillin acylase activity of aculeacin A acylase from Actinoplanes utahensis.

Jesús Torres-Bacete1, Daniel Hormigo, Maribel Stuart, Miguel Arroyo, Pedro Torres, María P Castillón, Carmen Acebal, José L García, Isabel de la Mata.   

Abstract

Aculeacin A acylase from Actinoplanes utahensis produced by Streptomyces lividans revealed acylase activities that are able to hydrolyze penicillin V and several natural aliphatic penicillins. Penicillin K was the best substrate, showing a catalytic efficiency of 34.79 mM(-1) s(-1). Furthermore, aculeacin A acylase was highly thermostable, with a midpoint transition temperature of 81.5 degrees C.

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Year:  2007        PMID： 17586674      PMCID： PMC1950969          DOI： 10.1128/AEM.00452-07

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  15 in total

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Authors:  M Arroyo; I de la Mata; C Acebal; M Pilar Castillón
Journal:  Appl Microbiol Biotechnol       Date:  2002-12-11       Impact factor: 4.813

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Journal:  Appl Microbiol Biotechnol       Date:  1999-12       Impact factor: 4.813

5.  Studies on aculeacin. I. Isolation and characterization of aculeacin A.

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Journal:  J Antibiot (Tokyo)       Date:  1977-04       Impact factor: 2.649

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

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7.  Determination of cephalosporin-C amidohydrolase activity with fluorescamine.

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Journal:  J Pharm Pharmacol       Date:  1989-02       Impact factor: 3.765

8.  Deacylation of echinocandin B by Actinoplanes utahensis.

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Journal:  J Antibiot (Tokyo)       Date:  1989-03       Impact factor: 2.649

9.  Synthesis of new analogs of echinocandin B by enzymatic deacylation and chemical reacylation of the echinocandin B peptide: synthesis of the antifungal agent cilofungin (LY121019).

Authors:  M Debono; B J Abbott; D S Fukuda; M Barnhart; K E Willard; R M Molloy; K H Michel; J R Turner; T F Butler; A H Hunt
Journal:  J Antibiot (Tokyo)       Date:  1989-03       Impact factor: 2.649

10.  Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus.

Authors:  L M Quirós; I Aguirrezabalaga; C Olano; C Méndez; J A Salas
Journal:  Mol Microbiol       Date:  1998-06       Impact factor: 3.501
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  9 in total

1.  Overexpression of penicillin V acylase from Streptomyces lavendulae and elucidation of its catalytic residues.

Authors:  Jesús Torres-Bacete; Daniel Hormigo; Raquel Torres-Gúzman; Miguel Arroyo; María Pilar Castillón; Luis José García; Carmen Acebal; Isabel de la Mata
Journal:  Appl Environ Microbiol       Date:  2015-02       Impact factor: 4.792

2.  The quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket.

Authors:  Marcel Bokhove; Pol Nadal Jimenez; Wim J Quax; Bauke W Dijkstra
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-22       Impact factor: 11.205

3.  Engineering the substrate specificity of a thermophilic penicillin acylase from thermus thermophilus.

Authors:  Leticia L Torres; Angel Cantero; Mercedes del Valle; Anabel Marina; Fernando López-Gallego; José M Guisán; José Berenguer; Aurelio Hidalgo
Journal:  Appl Environ Microbiol       Date:  2012-12-21       Impact factor: 4.792

4.  Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli.

Authors:  Leticia L Torres; Eloy R Ferreras; Angel Cantero; Aurelio Hidalgo; José Berenguer
Journal:  Microb Cell Fact       Date:  2012-08-09       Impact factor: 5.328

5.  Genome Sequence of Streptomyces exfoliatus DSMZ 41693, a Source of Poly(3-Hydroxyalkanoate)-Degrading Enzymes.

Authors:  Virginia Martínez; Daniel Hormigo; Carlos Del Cerro; Patricia Gómez de Santos; Javier García-Hidalgo; Miguel Arroyo; Auxiliadora Prieto; José Luis García; Isabel de la Mata
Journal:  Genome Announc       Date:  2014-02-06

6.  Draft Genome Sequence of Actinoplanes utahensis NRRL 12052, a Microorganism Involved in Industrial Production of Pharmaceutical Intermediates.

Authors:  Rodrigo Velasco-Bucheli; Carlos Del Cerro; Daniel Hormigo; Carmen Acebal; Miguel Arroyo; José L García; Isabel de la Mata
Journal:  Genome Announc       Date:  2015-01-08

7.  Genomic and transcriptomic survey of an endophytic fungus Calcarisporium arbuscula NRRL 3705 and potential overview of its secondary metabolites.

Authors:  Jin-Tao Cheng; Fei Cao; Xin-Ai Chen; Yong-Quan Li; Xu-Ming Mao
Journal:  BMC Genomics       Date:  2020-06-24       Impact factor: 3.969

8.  Importance of the latex-clearing protein (Lcp) for poly(cis-1,4-isoprene) rubber cleavage in Streptomyces sp. K30.

Authors:  Meral Yikmis; Alexander Steinbüchel
Journal:  Microbiologyopen       Date:  2012-03       Impact factor: 3.139

9.  Comparative Metagenomic Study of Rhizospheric and Bulk Mercury-Contaminated Soils in the Mining District of Almadén.

Authors:  Daniel González; Marina Robas; Vanesa Fernández; Marta Bárcena; Agustín Probanza; Pedro A Jiménez
Journal:  Front Microbiol       Date:  2022-03-07       Impact factor: 5.640
  9 in total

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