Literature DB >> 17586625

Genetic structure of the nadA and nadB antivirulence loci in Shigella spp.

Anne-Laure Prunier1, Raymond Schuch, Reinaldo E Fernández, Anthony T Maurelli.   

Abstract

Comparison of nadA and nadB in 14 Shigella strains and enteroinvasive Escherichia coli versus E. coli showed that at least one locus is altered in all strains. These observations explain the characteristic nicotinic acid auxotrophy of Shigella organisms and are consistent with the previously identified antivirulence nature of these genes for these pathogens.

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Year:  2007        PMID: 17586625      PMCID: PMC1951923          DOI: 10.1128/JB.00525-07

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  25 in total

1.  Pathoadaptive mutations: gene loss and variation in bacterial pathogens.

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Review 4.  Pathogenicity islands and the evolution of bacterial pathogens.

Authors:  C A Lee
Journal:  Infect Agents Dis       Date:  1996-01

5.  Molecular evolution of large virulence plasmid in Shigella clones and enteroinvasive Escherichia coli.

Authors:  R Lan; B Lumb; D Ryan; P R Reeves
Journal:  Infect Immun       Date:  2001-10       Impact factor: 3.441

6.  Pathoadaptive mutations that enhance virulence: genetic organization of the cadA regions of Shigella spp.

Authors:  W A Day; R E Fernández; A T Maurelli
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441

7.  A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.

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Journal:  Microbiol Rev       Date:  1989-03

8.  Involvement of a plasmid in the invasive ability of Shigella flexneri.

Authors:  P J Sansonetti; D J Kopecko; S B Formal
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9.  nadA and nadB of Shigella flexneri 5a are antivirulence loci responsible for the synthesis of quinolinate, a small molecule inhibitor of Shigella pathogenicity.

Authors:  Anne-Laure Prunier; Raymond Schuch; Reinaldo E Fernández; Karen L Mumy; Henrik Kohler; Beth A McCormick; Anthony T Maurelli
Journal:  Microbiology       Date:  2007-07       Impact factor: 2.777

10.  Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery.

Authors:  Fan Yang; Jian Yang; Xiaobing Zhang; Lihong Chen; Yan Jiang; Yongliang Yan; Xudong Tang; Jing Wang; Zhaohui Xiong; Jie Dong; Ying Xue; Yafang Zhu; Xingye Xu; Lilian Sun; Shuxia Chen; Huan Nie; Junping Peng; Jianguo Xu; Yu Wang; Zhenghong Yuan; Yumei Wen; Zhijian Yao; Yan Shen; Boqin Qiang; Yunde Hou; Jun Yu; Qi Jin
Journal:  Nucleic Acids Res       Date:  2005-11-07       Impact factor: 16.971

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  15 in total

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2.  Core and panmetabolism in Escherichia coli.

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Journal:  J Bacteriol       Date:  2011-01-14       Impact factor: 3.490

Review 3.  Exploring NAD+ metabolism in host-pathogen interactions.

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4.  A pathoadaptive deletion in an enteroaggregative Escherichia coli outbreak strain enhances virulence in a Caenorhabditis elegans model.

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Journal:  Infect Immun       Date:  2010-06-28       Impact factor: 3.441

5.  Cytosine chemoreceptor McpC in Pseudomonas putida F1 also detects nicotinic acid.

Authors:  Rebecca E Parales; Vasyl Nesteryuk; Jonathan G Hughes; Rita A Luu; Jayna L Ditty
Journal:  Microbiology (Reading)       Date:  2014-10-07       Impact factor: 2.777

Review 6.  Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion.

Authors:  Gunnar N Schroeder; Hubert Hilbi
Journal:  Clin Microbiol Rev       Date:  2008-01       Impact factor: 26.132

7.  Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci.

Authors:  Leonardo Sorci; Ian K Blaby; Irina A Rodionova; Jessica De Ingeniis; Sergey Tkachenko; Valérie de Crécy-Lagard; Andrei L Osterman
Journal:  J Bacteriol       Date:  2012-11-30       Impact factor: 3.490

8.  Experimental evidence for negative selection in the evolution of a Yersinia pestis pseudogene.

Authors:  Yi-Cheng Sun; B Joseph Hinnebusch; Creg Darby
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-03       Impact factor: 11.205

9.  Biogenesis and Homeostasis of Nicotinamide Adenine Dinucleotide Cofactor.

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10.  Genome-scale metabolic reconstructions of multiple Escherichia coli strains highlight strain-specific adaptations to nutritional environments.

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Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-25       Impact factor: 11.205

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