Literature DB >> 10354593

Pathoadaptive mutations: gene loss and variation in bacterial pathogens.

E V Sokurenko1, D L Hasty, D E Dykhuizen.   

Abstract

Pathogenicity-adaptive, or pathoadaptive, mutations represent a genetic mechanism for enhancing bacterial virulence without horizontal transfer of specific virulence factors. Pathoadaptive evolution can be important within single infections and for defining the population structure of a pathogenic species.

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Mesh：

Year:  1999        PMID： 10354593     DOI： 10.1016/s0966-842x(99)01493-6

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  88 in total

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