Shahzad I Mian1, Roni M Shtein, Ariana Nelson, David C Musch. 1. Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan 48105, USA. smian@umich.edu
Abstract
PURPOSE: To determine whether hinge position has an effect on corneal sensation and dry-eye symptoms after myopic laser in situ keratomileusis (LASIK) performed with the IntraLase femtosecond laser (IntraLase Corp.). SETTING: University-based academic practice, Ann Arbor, Michigan, USA. METHODS:Sixty-six consecutive eyes of 33 patients were prospectively evaluated in a randomized contralateral-eye study to compare the difference between superior-hinge and temporal-hinge locations after bilateral myopic LASIK with the IntraLase femtosecond laser. Central Cochet-Bonnet esthesiometry, the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer test with anesthesia, tear breakup time (TBUT), corneal fluorescein, and conjunctival lissamine green staining were evaluated preoperatively as well as 1 week and 1, 3, 6, and 12 months after surgery. RESULTS:Corneal sensation was reduced with both superior-hinged and temporal-hinged LASIK flaps 1 week and 1, 3, 6, and 12 months after surgery (P<.0001). There was no difference in corneal sensation between superior-hinged and temporal-hinged flaps at any time point. The OSDI score was increased in 22.6% of patients at 1 week and 21.9% at 1 month (P<.00001), and corneal fluorescein staining was increased in 18% at 1 week. There were no differences in the OSDI, Schirmer with anesthesia, TBUT, corneal fluorescein, or conjunctival lissamine green staining when preoperative values and hinge location were compared. CONCLUSIONS:Mild dry-eye disease was present early after myopic LASIK with the IntraLase laser. Hinge position had no effect on central corneal sensation or dry-eye disease.
RCT Entities:
PURPOSE: To determine whether hinge position has an effect on corneal sensation and dry-eye symptoms after myopic laser in situ keratomileusis (LASIK) performed with the IntraLase femtosecond laser (IntraLase Corp.). SETTING: University-based academic practice, Ann Arbor, Michigan, USA. METHODS: Sixty-six consecutive eyes of 33 patients were prospectively evaluated in a randomized contralateral-eye study to compare the difference between superior-hinge and temporal-hinge locations after bilateral myopic LASIK with the IntraLase femtosecond laser. Central Cochet-Bonnet esthesiometry, the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer test with anesthesia, tear breakup time (TBUT), corneal fluorescein, and conjunctival lissamine green staining were evaluated preoperatively as well as 1 week and 1, 3, 6, and 12 months after surgery. RESULTS:Corneal sensation was reduced with both superior-hinged and temporal-hinged LASIK flaps 1 week and 1, 3, 6, and 12 months after surgery (P<.0001). There was no difference in corneal sensation between superior-hinged and temporal-hinged flaps at any time point. The OSDI score was increased in 22.6% of patients at 1 week and 21.9% at 1 month (P<.00001), and corneal fluorescein staining was increased in 18% at 1 week. There were no differences in the OSDI, Schirmer with anesthesia, TBUT, corneal fluorescein, or conjunctival lissamine green staining when preoperative values and hinge location were compared. CONCLUSIONS: Mild dry-eye disease was present early after myopic LASIK with the IntraLase laser. Hinge position had no effect on central corneal sensation or dry-eye disease.
Authors: Fiona Stapleton; Carl Marfurt; Blanka Golebiowski; Mark Rosenblatt; David Bereiter; Carolyn Begley; Darlene Dartt; Juana Gallar; Carlos Belmonte; Pedram Hamrah; Mark Willcox Journal: Invest Ophthalmol Vis Sci Date: 2013-10-18 Impact factor: 4.799
Authors: Andrea Petznick; Annabel Chew; Reece C Hall; Cordelia Ml Chan; Mohamad Rosman; Donald Tan; Louis Tong; Jodhbir S Mehta Journal: Clin Ophthalmol Date: 2013-03-24