Literature DB >> 17584056

Dual action-based approaches to antibacterial agents.

John B Bremner1, Joseph I Ambrus, Siritron Samosorn.   

Abstract

This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs).

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Year:  2007        PMID： 17584056     DOI： 10.2174/092986707780831168

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN： 0929-8673            Impact factor:   4.530


  17 in total

1.  A Hybrid Drug Limits Resistance by Evading the Action of the Multiple Antibiotic Resistance Pathway.

Authors:  Kathy K Wang; Laura K Stone; Tami D Lieberman; Michal Shavit; Timor Baasov; Roy Kishony
Journal:  Mol Biol Evol       Date:  2015-11-03       Impact factor: 16.240

Review 2.  Challenges of antibacterial discovery.

Authors:  Lynn L Silver
Journal:  Clin Microbiol Rev       Date:  2011-01       Impact factor: 26.132

Review 3.  Antibiotic Hybrids: the Next Generation of Agents and Adjuvants against Gram-Negative Pathogens?

Authors:  Ronald Domalaon; Temilolu Idowu; George G Zhanel; Frank Schweizer
Journal:  Clin Microbiol Rev       Date:  2018-03-14       Impact factor: 26.132

Review 4.  New developments in aminoglycoside therapy and ototoxicity.

Authors:  Jing Xie; Andra E Talaska; Jochen Schacht
Journal:  Hear Res       Date:  2011-05-27       Impact factor: 3.208

5.  Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components.

Authors:  Danuta Tomkiewicz; Gabriele Casadei; Jonah Larkins-Ford; Terence I Moy; James Garner; John B Bremner; Frederick M Ausubel; Kim Lewis; Michael J Kelso
Journal:  Antimicrob Agents Chemother       Date:  2010-05-24       Impact factor: 5.191

6.  On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials.

Authors:  Naveen K Dolla; Chao Chen; Jonah Larkins-Ford; Rajmohan Rajamuthiah; Sakthimala Jagadeesan; Annie L Conery; Frederick M Ausubel; Eleftherios Mylonakis; John B Bremner; Kim Lewis; Michael J Kelso
Journal:  Aust J Chem       Date:  2015       Impact factor: 1.321

Review 7.  Novel Targets for Antimicrobials.

Authors:  Suchita Gupta; Vaishali Ravindra Undale; Kedar Lakhadive
Journal:  Turk J Pharm Sci       Date:  2020-10-30

8.  Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

Authors:  Joseph I Ambrus; Michael J Kelso; John B Bremner; Anthony R Ball; Gabriele Casadei; Kim Lewis
Journal:  Bioorg Med Chem Lett       Date:  2008-07-02       Impact factor: 2.823

9.  Antibacterial activity of berberine-NorA pump inhibitor hybrids with a methylene ether linking group.

Authors:  Siritron Samosorn; Bongkot Tanwirat; Nussara Muhamad; Gabriele Casadei; Danuta Tomkiewicz; Kim Lewis; Apichart Suksamrarn; Therdsak Prammananan; Karina C Gornall; Jennifer L Beck; John B Bremner
Journal:  Bioorg Med Chem       Date:  2009-04-19       Impact factor: 3.641

10.  Novel phytochemical-antibiotic conjugates as multitarget inhibitors of Pseudomononas aeruginosa GyrB/ParE and DHFR.

Authors:  Premkumar Jayaraman; Kishore R Sakharkar; ChuSing Lim; Mohammad Imran Siddiqi; Sarinder K Dhillon; Meena K Sakharkar
Journal:  Drug Des Devel Ther       Date:  2013-06-17       Impact factor: 4.162
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