Literature DB >> 17576595

The influence of resilience on fatigue in cancer patients undergoing radiation therapy (RT).

Bernhard Strauss1, Christina Brix, Sebastian Fischer, Karena Leppert, Jürgen Füller, Bernd Roehrig, Christine Schleussner, Thomas G Wendt.   

Abstract

PURPOSE: The primary goal of the study was to determine if resilience influences fatigue in a consecutive sample of cancer patients treated with radiotherapy (RT) at the beginning and at the end of the treatment.
METHODS: Out of an initial sample of 250 patients, 239 could be assessed at the beginning of their RT. Two hundred and eight patients were reassessed at the end of RT 4-8 weeks later. Measures comprised the Resilience Scale (RS), the Multidimensional Fatigue Inventory (MFI), and the SF-12 as a measure of health related Quality of Life (QoL). Medical data were continuously registered.
RESULTS: As hypothesized, the sample revealed higher scores in the MFI and lower scores in the SF-12 than normative samples. Resilience scores were higher than in the norm population. Fatigue increased during RT. Using multiple regression analyses, fatigue scores at the beginning of treatment were shown to be higher in inpatients and patients undergoing palliative treatment. Initial fatigue was best predicted by the patients' initial resilience scores. Changes of fatigue scores during RT depended on initial scores, decrease in Hb and the patients' experience with RT. Resilience could not be determined as a predictor of changes in fatigue during RT.
CONCLUSIONS: The study confirmed that fatigue is an important problem among RT patients. Resilience turned out to powerfully predict the patients' fatigue at least early in RT. This result is in line with other studies, showing resilience to be an important psychological predictor of QoL and coping in cancer patients. On the other hand, resilience seems to have little influence on treatment related fatigue during RT.

Entities:  

Mesh:

Year:  2007        PMID: 17576595     DOI: 10.1007/s00432-007-0195-z

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.322


  30 in total

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Review 5.  Radiotherapy-related fatigue.

Authors:  Barbara Alicja Jereczek-Fossa; Hugo Raul Marsiglia; Roberto Orecchia
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10.  The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue.

Authors:  E M Smets; B Garssen; B Bonke; J C De Haes
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  31 in total

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6.  Gender Differences in Predictors of Quality of Life at the Initiation of Radiation Therapy.

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8.  Determining the minimal clinically important difference criteria for the Multidimensional Fatigue Inventory in a radiotherapy population.

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Review 9.  Going to extremes: determinants of extraordinary response and survival in patients with cancer.

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10.  The Resilience of Indigenous Women of the U.S. Who Experience Cancer: Transcending Adversity.

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