Literature DB >> 17576417

Revisiting the ancient concept of botanical therapeutics.

Barbara M Schmidt1, David M Ribnicky, Peter E Lipsky, Ilya Raskin.   

Abstract

Mixtures of interacting compounds produced by plants may provide important combination therapies that simultaneously affect multiple pharmacological targets and provide clinical efficacy beyond the reach of single compound-based drugs. Developing innovative scientific methods for discovery, validation, characterization and standardization of these multicomponent botanical therapeutics is essential to their acceptance into mainstream medicine.

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Year:  2007        PMID: 17576417     DOI: 10.1038/nchembio0707-360

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


  78 in total

1.  Western healers in traditional Chinese medicine.

Authors:  Xue-Juan Li; Hong-Yu Zhang
Journal:  EMBO Rep       Date:  2008-02       Impact factor: 8.807

2.  Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

Authors:  Hong-Fang Ji; Xue-Juan Li; Hong-Yu Zhang
Journal:  EMBO Rep       Date:  2009-02-20       Impact factor: 8.807

3.  Molecular understanding and modern application of traditional medicines: triumphs and trials.

Authors:  Timothy W Corson; Craig M Crews
Journal:  Cell       Date:  2007-09-07       Impact factor: 41.582

4.  Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression.

Authors:  Zhipeng Wang; Haifeng Jin; Ruodan Xu; Qibing Mei; Daiming Fan
Journal:  Exp Mol Med       Date:  2009-10-31       Impact factor: 8.718

5.  A systems approach to traditional oriental medicine.

Authors:  Hyun Uk Kim; Jae Yong Ryu; Jong Ok Lee; Sang Yup Lee
Journal:  Nat Biotechnol       Date:  2015-03       Impact factor: 54.908

6.  Genome-Wide Prediction of Metabolic Enzymes, Pathways, and Gene Clusters in Plants.

Authors:  Pascal Schläpfer; Peifen Zhang; Chuan Wang; Taehyong Kim; Michael Banf; Lee Chae; Kate Dreher; Arvind K Chavali; Ricardo Nilo-Poyanco; Thomas Bernard; Daniel Kahn; Seung Y Rhee
Journal:  Plant Physiol       Date:  2017-02-22       Impact factor: 8.340

7.  Chloroform fraction of Serratulae chinensis S. Moore suppresses proliferation and induces apoptosis via the phosphatidylinositide 3-kinase/Akt pathway in human gastric cancer cells.

Authors:  Qiaoyan Cai; Jing Lin; Ling Zhang; Shan Lin; Jun Peng
Journal:  Oncol Lett       Date:  2018-03-28       Impact factor: 2.967

8.  Effects of traditional oriental medicines as anti-cytotoxic agents in radiotherapy.

Authors:  Wanyeon Kim; Jihoon Kang; Sungmin Lee; Buhyun Youn
Journal:  Oncol Lett       Date:  2017-04-18       Impact factor: 2.967

9.  MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages.

Authors:  Vummidigiridhar Premkumar; Moul Dey; Ruth Dorn; Ilya Raskin
Journal:  BMC Chem Biol       Date:  2010-04-12

10.  Bioactive equivalence of combinatorial components identified in screening of an herbal medicine.

Authors:  Peng Liu; Hua Yang; Fang Long; Hai-Ping Hao; Xiaojun Xu; Ying Liu; Xiao-Wei Shi; Dan-Dan Zhang; Hao-Chuan Zheng; Qian-Ying Wen; Wen-Wen Li; Hui Ji; Xi-Juan Jiang; Bo-Li Zhang; Lian-Wen Qi; Ping Li
Journal:  Pharm Res       Date:  2014-02-19       Impact factor: 4.200

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