Literature DB >> 17566197

Long-term outcomes in patients with treated childhood hydrocephalus.

Nalin Gupta1, Jeanna Park, Cynthia Solomon, Dory A Kranz, Margaret Wrensch, Yvonne W Wu.   

Abstract

OBJECT: The goal in this study was to determine the long-term effects of childhood hydrocephalus.
METHODS: A patient-reported survey completed by 1953 participants was used to collect data in a subgroup of 1459 individuals who had been treated for hydrocephalus in childhood. Data on shunt complications, including total shunt revisions and infections, were examined in those whose hydrocephalus had been diagnosed at least 10 years earlier (718 patients). Social and functional outcomes were examined in patients who were 20 years of age or older at the time of survey completion (403 individuals). Specific questions addressed the presence of depression, the patient's marital status, independent living arrangements, and the educational level attained. Shunt complications were common; 54% of patients had four or more shunt revisions, and 9% had three or more shunt infections. Depression requiring treatment occurred in 45% of participants. Other measures of social functioning all reflected a major impact of childhood hydrocephalus. In general, a worse outcome was found in patients whose hydrocephalus was diagnosed before 18 months of age.
CONCLUSIONS: The lifelong morbidity associated with shunt placement to treat childhood hydrocephalus is substantial, and it includes shunt-related complications and comorbidities that adversely affect social functioning.

Entities:  

Mesh:

Year:  2007        PMID: 17566197     DOI: 10.3171/ped.2007.106.5.334

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  19 in total

1.  Changes of White Matter Diffusion Anisotropy in Response to a 6-Week iPad Application-Based Occupational Therapy Intervention in Children with Surgically Treated Hydrocephalus: A Pilot Study.

Authors:  Weihong Yuan; Karen Harpster; Blaise V Jones; Joshua S Shimony; Robert C McKinstry; Nicole Weckherlin; Stephanie S Powell; Holly Barnard; Jack Engsberg; Darren S Kadis; Jonathan Dodd; Mekibib Altaye; David D Limbrick; Scott K Holland; Sarah M Simpson; Sarah Bidwell; Francesco T Mangano
Journal:  Neuropediatrics       Date:  2016-07-20       Impact factor: 1.947

Review 2.  Ventriculosinus shunt.

Authors:  Ahmed K Toma; Andrew Tarnaris; Neil D Kitchen; Laurence D Watkins
Journal:  Neurosurg Rev       Date:  2010-02-23       Impact factor: 3.042

Review 3.  Who will care for me next? Transitioning to adulthood with hydrocephalus.

Authors:  Tamara D Simon; Sara Lamb; Nancy A Murphy; Bonnie Hom; Marion L Walker; Edward B Clark
Journal:  Pediatrics       Date:  2009-10-19       Impact factor: 7.124

Review 4.  Cerebrospinal Fluid Shunting Complications in Children.

Authors:  Brian W Hanak; Robert H Bonow; Carolyn A Harris; Samuel R Browd
Journal:  Pediatr Neurosurg       Date:  2017-03-02       Impact factor: 1.162

Review 5.  Quality of life in childhood hydrocephalus: a review.

Authors:  Abhaya V Kulkarni
Journal:  Childs Nerv Syst       Date:  2010-04-02       Impact factor: 1.475

6.  Implementing a digital real-time Hydrocephalus and Shunt Registry to evaluate contemporary pattern of care and surgical outcome in pediatric hydrocephalus.

Authors:  Hans Christoph Bock; Maximilian Kanzler; Ulrich-Wilhelm Thomale; Hans Christoph Ludwig
Journal:  Childs Nerv Syst       Date:  2017-11-09       Impact factor: 1.475

7.  Very long-term follow-up of adults treated in infancy for hydrocephalus.

Authors:  Eva-Karin Persson; Barbro Lindquist; Paul Uvebrant; Elisabeth Fernell
Journal:  Childs Nerv Syst       Date:  2011-06-24       Impact factor: 1.475

8.  Long-term mortality rates in pediatric hydrocephalus-a retrospective single-center study.

Authors:  Matthias Gmeiner; Helga Wagner; Christoph Zacherl; Petra Polanski; Christian Auer; Willem J R van Ouwerkerk; Kurt Holl
Journal:  Childs Nerv Syst       Date:  2016-10-20       Impact factor: 1.475

9.  A MATHEMATICAL ANALYSIS OF PHYSIOLOGICAL AND MOLECULAR MECHANISMS THAT MODULATE PRESSURE GRADIENTS AND FACILITATE VENTRICULAR EXPANSION IN HYDROCEPHALUS.

Authors:  Kathleen P Wilkie; Gurjit Nagra; Miles Johnston
Journal:  Int J Numer Anal Model B       Date:  2012

10.  Treatment of abdominal pseudocysts and associated ventricuoperitoneal shunt failure.

Authors:  Emily Dzongowski; Kamary Coriolano; Sandrine de Ribaupierre; Sarah A Jones
Journal:  Childs Nerv Syst       Date:  2017-10-09       Impact factor: 1.475

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