Literature DB >> 17566142

Adherence to multiple drug therapies: refill adherence to concomitant use of diabetes and asthma/COPD medication.

Kristin Krigsman1, J Lars G Nilsson, Lena Ring.   

Abstract

PURPOSE: To investigate whether patients with drugs for two chronic diseases, type 2 diabetes and asthma/chronic obstructive pulmonary diseases (COPD), showed the same refill adherence pattern in relation to their drug treatments during a 3-year period.
METHODS: Patients 50 years and older who had been dispensed diabetes and asthma/COPD drugs in the county of Jämtland during 2001-2003 were included. The refill adherence was calculated based either on prescribed dosage or defined daily dose (DDD). A patient profile graph for each patient was constructed including the date of each dispensation and the time period covered by the dispensed drugs. For each patient, the dispensation pattern and the treatment persistency over time were determined.
RESULTS: In total, 56 patients were included in the study. Satisfactory refill adherence was found for 68% of the repeat prescriptions for diabetes drugs and for 42% of the repeat prescriptions for asthma/COPD drugs. About half (52%; 29/56) of the patients showed the same dispensation patterns for both diabetes and asthma/COPD drugs, and 86% (25/29) of these patients had a satisfactory refill adherence. However, there was no correlation or agreement regarding the dispensation patterns for diabetes and asthma/COPD drugs.
CONCLUSIONS: Patients showed higher refill adherence for their diabetes drugs than their asthma/COPD drugs. Our hypothesis that patients with satisfactory refill adherence to antihyperglycaemic drugs would also have satisfactory refill adherence to asthma/COPD drugs, was not supported.

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Mesh:

Year:  2007        PMID: 17566142     DOI: 10.1002/pds.1433

Source DB:  PubMed          Journal:  Pharmacoepidemiol Drug Saf        ISSN: 1053-8569            Impact factor:   2.890


  19 in total

1.  Exploring variables associated with medication non-adherence in patients with COPD.

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2.  Factors affecting satisfaction with education program for chronic airway disease in primary care settings.

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3.  Predictors of adherence to inhaled medications among Veterans with COPD.

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4.  Individual patients hold different beliefs to prescription medications to which they persist vs nonpersist and persist vs nonfulfill.

Authors:  Colleen A McHorney; Abhijit S Gadkari
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6.  Understanding rational non-adherence to medications. A discrete choice experiment in a community sample in Australia.

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Review 7.  Medication adherence issues in patients treated for COPD.

Authors:  Ruben D Restrepo; Melissa T Alvarez; Leonard D Wittnebel; Helen Sorenson; Richard Wettstein; David L Vines; Jennifer Sikkema-Ortiz; Donna D Gardner; Robert L Wilkins
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2008

8.  Adherence to Inhaled Medications and its Effect on Healthcare Utilization and Costs Among High-Grade Chronic Obstructive Pulmonary Disease Patients.

Authors:  Jee-Ae Kim; Min Kyoung Lim; Kunil Kim; JuHee Park; Chin Kook Rhee
Journal:  Clin Drug Investig       Date:  2018-04       Impact factor: 2.859

9.  Structural equation modeling of the proximal-distal continuum of adherence drivers.

Authors:  Colleen A McHorney; Ning Jackie Zhang; Timothy Stump; Xiaoquan Zhao
Journal:  Patient Prefer Adherence       Date:  2012-11-09       Impact factor: 2.711

10.  Effect of a network system for providing proper inhalation technique by community pharmacists on clinical outcomes in COPD patients.

Authors:  Masaya Takemura; Katsumi Mitsui; Masako Ido; Masataka Matsumoto; Misuzu Koyama; Daiki Inoue; Kazufumi Takamatsu; Ryo Itotani; Manabu Ishitoko; Shinko Suzuki; Kensaku Aihara; Minoru Sakuramoto; Hitoshi Kagioka; Motonari Fukui
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2013-05-09
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