Literature DB >> 19636490

Anticholinergic drug use for overactive bladder in Sweden: a nationwide pharmacoepidemiological study.

Daniel Altman1, Fredrik Granath, Anders Mattiasson, Christian Falconer.   

Abstract

INTRODUCTION AND HYPOTHESIS: Nationwide use and costs of anticholinergic drug for overactive bladder are unknown.
METHODS: We performed a nationwide study based on the Swedish Register on Prescribed Pharmaceuticals.
RESULTS: From 2000 to 2007, there was a 68.8% increase in dispensed anticholinergic drugs in a population of 9 million. More than 93 million DDDs (calculated average maintenance dose per day) of anticholinergic drugs were dispensed corresponding to an overall DDD/TID (DDD per 1,000 inhabitants per day) of 3.5 per 1,000 persons per year. Approximately two thirds of anticholinergic drugs were prescribed to women, regardless of drug type. In 2007, the cost for anticholinergic drugs was 22 million <euro> of which tolterodine comprised 70.8%. Solifenacin and darifenacin steadily increased their DDD/TIDs after market introduction.
CONCLUSIONS: In this nationwide study, there was a 70% increased rate of expedited prescriptions of anticholinergic drugs for the treatment of overactive bladder in a relatively stable population.

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Year:  2009        PMID: 19636490     DOI: 10.1007/s00192-009-0957-z

Source DB:  PubMed          Journal:  Int Urogynecol J Pelvic Floor Dysfunct


  17 in total

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Authors:  G Willy Davila; Jonathan S Starkman; Roger R Dmochowski
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3.  Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study.

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Review 4.  Tolterodine--a new bladder selective muscarinic receptor antagonist: preclinical pharmacological and clinical data.

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Review 5.  Oxybutynin and the overactive bladder.

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Authors:  Debra E Irwin; Ian Milsom; Zoe Kopp; Paul Abrams
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Review 10.  Anticholinergic drugs versus placebo for overactive bladder syndrome in adults.

Authors:  G Nabi; J D Cody; G Ellis; P Herbison; J Hay-Smith
Journal:  Cochrane Database Syst Rev       Date:  2006-10-18
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  5 in total

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4.  Patterns of use of antimuscarinic drugs to treat overactive bladder in Denmark, Sweden, and the United Kingdom.

Authors:  Andrea V Margulis; Marie Linder; Alejandro Arana; Anton Pottegård; Ina Anveden Berglind; Christine L Bui; Nina Sahlertz Kristiansen; Shahram Bahmanyar; Lisa J McQuay; Willem Jan Atsma; Kwame Appenteng; Milbhor D'Silva; Susana Perez-Gutthann; Jesper Hallas
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Authors:  Yu-Hua Lin; Wei-Yi Huang; Chi-Chih Chang; Yu-Fen Chen; Ling-Ying Wu; Hong-Chiang Chang; Kuo-How Huang
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  5 in total

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