PURPOSE: Epilepsy and malnutrition are both important public health problems in sub-Saharan Africa. A relationship between epilepsy and malnutrition has been suspected for many years. Our objective was to investigate the association between epilepsy and malnutrition in Djidja, Benin. METHODS: A matched population-based cross-sectional case-control survey was performed: cases (patients with epilepsy) were matched to controls according to sex, age +/- 5 years, and village of residence. The World Health Organization's criteria for malnutrition was used. Anthropometric measurements (weight, height, mid arm upper circumference, triceps skinfold thickness) were taken. Bioelectrical impedance analysis, a standardized food and social questionnaire and a clinical examination were done. Statistical analysis (conditional logistic regression) was performed using SAS 8.0. RESULTS: A total of 131 cases and 262 controls were included. The prevalence of malnutrition was higher in cases than in controls (22.1% vs. 9.2%, p = 0.0006). Social factors were significantly different between cases and controls. Feeding difficulties were more frequent and health status was worse in cases. Seven variables were associated with epilepsy: (i) nutritional factors: mid arm upper circumference (prevalence odds ratio (pOR) = 0.7, CI: 0.6-0.9), cereal consumption <3 times during the 3 days before the study (pOR = 4.2, CI: 1.8-10.0), <3 meals/day (pOR = 4.2, CI: 1.6-10.9), tooth decay (pOR = 2.9, CI: 1.1-7.4), food taboos (pOR = 25.0, CI: 8.3-100.0), (ii) social factors: surrogate respondent (pOR = 16.8, CI: 3.1-90.3) and no second job (pOR = 7.1, CI: 2.3-22.3). CONCLUSION: Epilepsy and nutritional status are linked in sub-Saharan Africa. Programs to improve the nutritional status of people with epilepsy are needed.
PURPOSE:Epilepsy and malnutrition are both important public health problems in sub-Saharan Africa. A relationship between epilepsy and malnutrition has been suspected for many years. Our objective was to investigate the association between epilepsy and malnutrition in Djidja, Benin. METHODS: A matched population-based cross-sectional case-control survey was performed: cases (patients with epilepsy) were matched to controls according to sex, age +/- 5 years, and village of residence. The World Health Organization's criteria for malnutrition was used. Anthropometric measurements (weight, height, mid arm upper circumference, triceps skinfold thickness) were taken. Bioelectrical impedance analysis, a standardized food and social questionnaire and a clinical examination were done. Statistical analysis (conditional logistic regression) was performed using SAS 8.0. RESULTS: A total of 131 cases and 262 controls were included. The prevalence of malnutrition was higher in cases than in controls (22.1% vs. 9.2%, p = 0.0006). Social factors were significantly different between cases and controls. Feeding difficulties were more frequent and health status was worse in cases. Seven variables were associated with epilepsy: (i) nutritional factors: mid arm upper circumference (prevalence odds ratio (pOR) = 0.7, CI: 0.6-0.9), cereal consumption <3 times during the 3 days before the study (pOR = 4.2, CI: 1.8-10.0), <3 meals/day (pOR = 4.2, CI: 1.6-10.9), tooth decay (pOR = 2.9, CI: 1.1-7.4), food taboos (pOR = 25.0, CI: 8.3-100.0), (ii) social factors: surrogate respondent (pOR = 16.8, CI: 3.1-90.3) and no second job (pOR = 7.1, CI: 2.3-22.3). CONCLUSION:Epilepsy and nutritional status are linked in sub-Saharan Africa. Programs to improve the nutritional status of people with epilepsy are needed.
Authors: S Pilleron; J-C Desport; P Jésus; P Mbelesso; B Ndamba-Bandzouzi; J-F Dartigues; J-P Clément; P-M Preux; M Guerchet Journal: J Nutr Health Aging Date: 2015-06 Impact factor: 4.075
Authors: Jane J Rogathe; Jim Todd; Ewan Hunter; Richard Walker; Antony Ngugi; Charles Newton; Kathryn Burton Journal: Epilepsy Res Date: 2014-07-06 Impact factor: 3.045
Authors: Symon M Kariuki; William Matuja; Albert Akpalu; Angelina Kakooza-Mwesige; Martin Chabi; Ryan G Wagner; Myles Connor; Eddie Chengo; Anthony K Ngugi; Rachael Odhiambo; Christian Bottomley; Steven White; Josemir W Sander; Brian G R Neville; Charles R J C Newton; Rhian Twine; F Xavier Gómez Olivé; Mark Collinson; Kathleen Kahn; Stephen Tollman; Honratio Masanja; Alexander Mathew; George Pariyo; Stefan Peterson; Donald Ndyomughenyi; Evasius Bauni; Gathoni Kamuyu; Victor Mung'ala Odera; James O Mageto; Ken Ae-Ngibise; Bright Akpalu; Francis Agbokey; Patrick Adjei; Seth Owusu-Agyei; Immo Kleinschmidt; Victor C K Doku; Peter Odermatt; Thomas Nutman; Patricia Wilkins; John Noh Journal: Epilepsia Date: 2013-10-07 Impact factor: 5.864
Authors: Anthony K Ngugi; Christian Bottomley; Immo Kleinschmidt; Ryan G Wagner; Angelina Kakooza-Mwesige; Kenneth Ae-Ngibise; Seth Owusu-Agyei; Honorati Masanja; Gathoni Kamuyu; Rachael Odhiambo; Eddie Chengo; Josemir W Sander; Charles R Newton Journal: Lancet Neurol Date: 2013-01-31 Impact factor: 44.182