Literature DB >> 17565478

[Rational treatment of first-degree burns].

E Proksch1, J-M Jensen, A Crichton-Smith, A Fowler, J Clitherow.   

Abstract

First-degree burns are the most common type of burn, but are often inadequately treated. The methods of treatment and the course of healing are poorly documented owing to the fact that first-degree burns are generally not considered to be a serious injury. First-degree burns can be caused by thermal injury or UV irradiation (sunburn). The pathophysiology and the therapeutic approach are similar, although the damage follows a different time course for each injury--immediate damage after contact with hot objects, liquids or fire, delayed damage after sun exposure. After initial cooling with water, aqueous emulsions with small amounts of well-tolerated lipids (O/W emulsions) are best suited for treating first-degree burns or sunburn. Water evaporates producing cooling and reducing inflammation; the lipids accelerate the repair of the damaged skin barrier and reduce drying. Foam sprays and lotions are ideal because they are easy and painless to apply. The use of topical corticosteroids is not recommended, as superiority to the vehicle has not been shown.

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Year:  2007        PMID: 17565478     DOI: 10.1007/s00105-007-1364-3

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  36 in total

Review 1.  Management of acute sunburn.

Authors:  Amy Han; Howard I Maibach
Journal:  Am J Clin Dermatol       Date:  2004       Impact factor: 7.403

Review 2.  Evidence-based management of patients with burns.

Authors:  A Phipps
Journal:  J Wound Care       Date:  1998-06       Impact factor: 2.072

3.  Artificial barrier repair in wounds by semi-occlusive foils reduced wound contraction and enhanced cell migration and reepithelization in mouse skin.

Authors:  Michael Schunck; Claudia Neumann; Ehrhardt Proksch
Journal:  J Invest Dermatol       Date:  2005-11       Impact factor: 8.551

4.  Is prolonged and excessive cooling of a scalded wound effective?

Authors:  Y Sawada; S Urushidate; T Yotsuyanagi; K Ishita
Journal:  Burns       Date:  1997-02       Impact factor: 2.744

5.  Cooling the burn wound: evaluation of different modalites.

Authors:  V Jandera; D A Hudson; P M de Wet; P M Innes; H Rode
Journal:  Burns       Date:  2000-05       Impact factor: 2.744

6.  The effects of ultraviolet light and certain drugs on La-bearing Langerhans cells in murine epidermis.

Authors:  J J Nordlund; A E Ackles; A B Lerner
Journal:  Cell Immunol       Date:  1981-05-01       Impact factor: 4.868

Review 7.  Topical agents in burn and wound care.

Authors:  R S Ward; J R Saffle
Journal:  Phys Ther       Date:  1995-06

Review 8.  [Regulation of the epidermal permeability barrier by lipids and hyperproliferation].

Authors:  E Proksch
Journal:  Hautarzt       Date:  1992-06       Impact factor: 0.751

9.  Efficacy of dexpanthenol in skin protection against irritation: a double-blind, placebo-controlled study.

Authors:  Kathrin Biro; Diamant Thaçi; Falk R Ochsendorf; Roland Kaufmann; Wolf-Henning Boehncke
Journal:  Contact Dermatitis       Date:  2003-08       Impact factor: 6.600

10.  Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.

Authors:  A Köck; T Schwarz; R Kirnbauer; A Urbanski; P Perry; J C Ansel; T A Luger
Journal:  J Exp Med       Date:  1990-12-01       Impact factor: 14.307

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