Literature DB >> 175651

Toxicity and metabolism of methyl n-butyl ketone.

M S Abdel-Rahman, L B Hetland, D Couri.   

Abstract

MEK (2-butanone) when combined with MBK (2-hexanone) markedly enhanced MBK neurotoxicity. MBK in rat plasma after exposure to MBK/MEK increased with time. Metabolites of MBK identified in blood and urine of rats and guinea pigs were 2-hexanol and 2,5-hexanedione.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 175651     DOI： 10.1080/0002889768507418

Source DB:  PubMed          Journal:  Am Ind Hyg Assoc J        ISSN： 0002-8894


  21 in total

1.  Urinary excretion of n-hexane metabolites in rats and humans.

Authors:  L Perbellini; F Brugnone; G Pastorello; L Grigolini
Journal:  Int Arch Occup Environ Health       Date:  1979-01-15       Impact factor: 3.015

2.  Metabolic interaction between n-hexane and toluene in vivo and in vitro.

Authors:  L Perbellini; R Leone; M E Fracasso; F Brugnone; M S Venturini
Journal:  Int Arch Occup Environ Health       Date:  1982       Impact factor: 3.015

3.  An experimental study on the combined effects of n-hexane and toluene on the peripheral nerve of the rat.

Authors:  Y Takeuchi; Y Ono; N Hisanaga
Journal:  Br J Ind Med       Date:  1981-02

4.  Urinary excretion of the metabolites of n-hexane and its isomers during occupational exposure.

Authors:  L Perbellini; F Brugnone; G Faggionato
Journal:  Br J Ind Med       Date:  1981-02

5.  Changes in urinary n-hexane metabolites by co-exposure to various concentrations of methyl ethyl ketone and fixed n-hexane levels.

Authors:  E Shibata; J Huang; Y Ono; N Hisanaga; M Iwata; I Saito; Y Takeuchi
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153

6.  Experimental study on the enhancement of the neurotoxicity of methyl n-butyl ketone by non-neurotoxic aliphatic monoketones.

Authors:  J Misumi; M Nagano
Journal:  Br J Ind Med       Date:  1985-03

7.  A study on biological monitoring of n-hexane exposure.

Authors:  M Iwata; Y Takeuchi; N Hisanaga; Y Ono
Journal:  Int Arch Occup Environ Health       Date:  1983       Impact factor: 3.015

8.  n-Hexane-induced changes in nerve conduction velocities and somatosensory evoked potentials.

Authors:  A Mutti; F Ferri; G Lommi; S Lotta; S Lucertini; I Franchini
Journal:  Int Arch Occup Environ Health       Date:  1982       Impact factor: 3.015

9.  Neurophysiological studies on the relation between the structural properties and neurotoxicity of aliphatic hydrocarbon compounds in rats.

Authors:  J Misumi; M Nagano
Journal:  Br J Ind Med       Date:  1984-11

10.  Detection of 2,5-hexanedione in the urine of persons not exposed to n-hexane.

Authors:  N Fedtke; H M Bolt
Journal:  Int Arch Occup Environ Health       Date:  1986       Impact factor: 3.015
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.