| Literature DB >> 17560753 |
M E Fernyhough1, E Okine, G Hausman, J L Vierck, M V Dodson.
Abstract
In this document, we have integrated knowledge about two major cellular markers found in cells of the adipocyte lineage (an adipogenic marker and a metabolic marker). This review provides information as to how differentiation of a cell (such as an adipofibroblast, fibroblast or preadipocyte) to become a viable (and new) adipocyte is under different regulation than that experienced by an immature adipocyte that is just beginning to accumulate lipid. The differentiation, prior to lipid-filling, involves PPARgamma. Subsequently, lipid-filling of the adipocyte relies on a late subset of genes and, depending on depot specificity, involves GLUT-4 or any number of other metabolic markers.Entities:
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Year: 2007 PMID： 17560753 DOI： 10.1016/j.domaniend.2007.05.001
Source DB: PubMed Journal: Domest Anim Endocrinol ISSN： 0739-7240 Impact factor: 2.290