Literature DB >> 17551203

A new gamma-polymorph of chlorpropamide: 4-chloro-N-(propylaminocarbonyl)benzenesulfonamide.

Tatiana N Drebushchak1, Nikita V Chukanov, Elena V Boldyreva.   

Abstract

The structure of a new polymorph of the title compound, C(10)H(13)ClN(2)O(3)S, known as the antidiabetic drug chlorpropamide, is monoclinic, in contrast with the two previously described orthorhombic alpha- and beta-forms. The molecules in the gamma-polymorph are linked into bands by hydrogen bonds similar to those in the alpha-polymorph. The conformation of the molecules in the gamma-form is close to that in the beta-polymorph.

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Year:  2007        PMID: 17551203     DOI: 10.1107/S010827010701952X

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN: 0108-2701            Impact factor:   1.172


  2 in total

1.  Polymorphism in phenobarbital: discovery of a new polymorph and crystal structure of elusive form V.

Authors:  Saikat Roy; N Rajesh Goud; Adam J Matzger
Journal:  Chem Commun (Camb)       Date:  2016-03-21       Impact factor: 6.222

2.  Nonamorphism in flufenamic acid and a new record for a polymorphic compound with solved structures.

Authors:  Vilmalí López-Mejías; Jeff W Kampf; Adam J Matzger
Journal:  J Am Chem Soc       Date:  2012-06-12       Impact factor: 15.419

  2 in total

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